• ホーム
• 研究業績
• 原著論文

原著論文

2025年

• Identification of α-galactosylceramide as an endogenous mammalian antigen for iNKT cells.
  Hosono Y, Tomiyasu N, Kasai H, Ishikawa E, Takahashi M, Imamura A, Ishida H, Compostella F, Kida H, Kumanogoh A, Bamba T, Izumi Y, Yamasaki S.
  J Exp Med. 2025 Feb 3;222(2):e20240728.
• NHERF2 as a Novel Biomarker for Distinguishing MAC Pulmonary Disease from Tuberculosis Based on Proteome Analysis of Serum Extracellular Vesicles.
  Naito M, Takeda Y, Edahiro R, Shirai Y, Enomoto T, Nakayama M, Nojima S, Nogami-Ito M, Mori M, Yano Y, Matsuki T, Yoshimura H, Hara R, Yamamoto M, Masuhiro K, Naito Y, Koyama S, Iwahori K, Nagatomo I, Shiroyama T, Miyake K, Hirata H, Hase H, Tsujikawa K, Ueda K, Kumanogoh A.
  Int J Mol Sci. 2025 Jan 29;26(3):1155.
• Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells.
  Toghani D, Gupte S, Zeng S, Mahammadov E, Crosse EI, Seyedhassantehrani N, Burns C, Gravano D, Radtke S, Kiem HP, Rodriguez S, Carlesso N, Pradeep A, Georgiades A, Lucas F, Wilson NK, Kinston SJ, Göttgens B, Zong L, Beerman I, Park B, Janssens DH, Jones D, Toghani A, Nerlov C, Pietras EM, Mesnieres M, Maes C, Kumanogoh A, Worzfeld T, Cheong JG, Josefowicz SZ, Kharchenko P, Scadden DT, Scialdone A, Spencer JA, Silberstein L.
  Nat Aging. 2025 Jan 29. doi: 10.1038/s43587-024-00798-7.
• Enhancing the efficacy of near-infrared photoimmunotherapy through intratumoural delivery of CD44-targeting antibody-photoabsorber conjugates.
  Adachi Y, Miyake K, Ohira K, Satoh S, Masuhiro K, Edahiro R, Shirai Y, Naito M, Naito Y, Shiroyama T, Koyama S, Hirata H, Iwahori K, Nagatomo I, Takeda Y, Kumanogoh A.
  EBioMedicine. 2025 Jan 22;112:105566.
• Intestinal Foxl1+ cell-derived CXCL12 maintains epithelial homeostasis by modulating cellular metabolism.
  Yagita-Sakamaki M, Ito T, Sakaguchi T, Shimma S, Li B, Okuzaki D, Motooka D, Nakamura S, Hase K, Fukusaki E, Kikuchi A, Nagasawa T, Kumanogoh A, Takeda K, Kayama H.
  Int Immunol. 2025 Jan 8:dxae068
• Blood DNA virome associates with autoimmune diseases and COVID-19.
  Sasa N, Kojima S, Koide R, Hasegawa T, Namkoong H, Hirota T, Watanabe R, Nakamura Y, Oguro-Igashira E, Ogawa K, Yata T, Sonehara K, Yamamoto K, Kishikawa T, Sakaue S, Edahiro R, Shirai Y, Maeda Y, Nii T, Chubachi S, Tanaka H, Yabukami H, Suzuki A, Nakajima K, Arase N, Okamoto T, Nishikawa R, Namba S, Naito T, Miyagawa I, Tanaka H, Ueno M, Ishitsuka Y, Furuta J, Kunimoto K, Kajihara I, Fukushima S, Miyachi H, Matsue H, Kamata M, Momose M, Bito T, Nagai H, Ikeda T, Horikawa T, Adachi A, Matsubara T, Ikumi K, Nishida E, Nakagawa I, Yagita-Sakamaki M, Yoshimura M, Ohshima S, Kinoshita M, Ito S, Arai T, Hirose M, Tanino Y, Nikaido T, Ichiwata T, Ohkouchi S, Hirano T, Takada T, Tazawa R, Morimoto K, Takaki M, Konno S, Suzuki M, Tomii K, Nakagawa A, Handa T, Tanizawa K, Ishii H, Ishida M, Kato T, Takeda N, Yokomura K, Matsui T, Uchida A, Inoue H, Imaizumi K, Goto Y, Kida H, Fujisawa T, Suda T, Yamada T, Satake Y, Ibata H, Saigusa M, Shirai T, Hizawa N, Nakata K; Japan COVID-19 Task Force; Imafuku S, Tada Y, Asano Y, Sato S, Nishigori C, Jinnin M, Ihn H, Asahina A, Saeki H, Kawamura T, Shimada S, Katayama I, Poisner HM, Mack TM, Bick AG, Higasa K, Okuno T, Mochizuki H, Ishii M, Koike R, K…See abstract for full author list ➔
  Nat Genet. 2025 Jan;57(1):65-79.
• Increased angiopoietin-1 improves nailfold capillary morphology in patients with systemic sclerosis.
  Shima Y, Watanabe A, Inoue N, Maruyama T, Kunitomo E, Matsushima Y, Kumanogoh A.
  Microvasc Res. 2025 Jan;157:104761.

2024年

• Downregulation of semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis.
  Kume M, Koguchi-Yoshioka H, Nakai S, Matsumura Y, Tanemura A, Yokoi K, Matsuda S, Nakamura Y, Otani N, Taminato M, Tomita K, Kubo T, Wataya-Kaneda M, Kumanogoh A, Fujimoto M, Watanabe R.
  Elife. 2024 Dec 31;13:RP97654.
• CAR-NK cells derived from cord blood originate mainly from CD56^-CD7⁺CD34^-HLA-DR^-Lin^- NK progenitor cells.
  Wibowo T, Kogue Y, Ikeda S, Yaga M, Tachikawa M, Suga M, Kida S, Shibata K, Tsutsumi K, Murakami H, Ueda Y, Kato H, Fukushima K, Fujita J, Ueda T, Kusakabe S, Hino A, Ichii M, Imai C, Okuzaki D, Kumanogoh A, Hosen N.
  Mol Ther Methods Clin Dev. 2024 Nov 12;32(4):101374.
• Clonal landscape of autoantibody-secreting plasmablasts in COVID-19 patients.
  Sakakibara S, Liu YC, Ishikawa M, Edahiro R, Shirai Y, Haruna S, El Hussien MA, Xu Z, Li S, Yamaguchi Y, Murakami T, Morita T, Kato Y, Hirata H, Takeda Y, Sugihara F, Naito Y, Motooka D, Tsai CY, Ono C, Matsuura Y, Wing JB, Matsumoto H, Ogura H, Okada M, Kumanogoh A, Okada Y, Standley DM, Kikutani H, Okuzaki D.
  Life Sci Alliance. 2024 Sep 17;7(12):e202402774.
• Variability in non-tumor areas of colorectal cancer patients as revealed by endoscopic intestinal step biopsies.
  Ikuta S, Saito Y, Takata S, Nakatani Y, Nagatomo I, Shiba S, Takeda Y, Totoki Y, Mizutani S, Sunakawa H, Ikematsu H, Takamaru H, Kumanogoh A, Yachida S.
  Mol Cancer. 2024 Nov 7;23(1):249.
• Spontaneous high clonal expansion of Wilms' tumor gene 1-specific cytotoxic T-lymphocytes in patients with Wilms' tumor gene 1-expressing solid tumor.
  Morimoto S, Tanaka Y, Nakata J, Fujiki F, Hasegawa K, Nakajima H, Nishida S, Tsuboi A, Hosen N, Kagawa N, Maruno M, Myoui A, Enomoto T, Izumoto S, Sekimoto M, Hashimoto N, Yoshimine T, Kumanogoh A, Oji Y, Oka Y, Sugiyama H.
  Cancer Immunol Immunother. 2024 Nov 7;74(1):15.
• Variability of macrolide-resistant profile in Mycobacterium avium complex pulmonary disease.
  Fukushima K, Matsumoto Y, Abe Y, Hashimoto K, Motooka D, Kitada S, Saito H, Komukai S, Fukui E, Niitsu T, Nabeshima H, Nagahama Y, Yamauchi J, Nitta T, Nii T, Matsuki T, Tsujino K, Miki K, Shintani Y, Kumanogoh A, Akira S, Nakamura S, Kida H.
  Antimicrob Agents Chemother. 2024 Nov 6;68(11):e0121324.
• The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells.
  Oguro-Igashira E, Murakami M, Mori R, Kuwahara R, Kihara T, Kohara M, Fujiwara M, Motooka D, Okuzaki D, Arase M, Toyota H, Peng S, Ogino T, Kitabatake Y, Morii E, Hirota S, Ikeuchi H, Umemoto E, Kumanogoh A, Takeda K.
  Proc Natl Acad Sci U S A. 2024 Oct 29;121(44):e2318767121.
• MicroRNA-130a-3p regulates osimertinib resistance by targeting runt-related transcription factor 3 in lung adenocarcinoma.
  Shintani T, Shun YT, Toyozumi Y, Ikemura K, Shiroyama T, Nagatomo I, Jingushi K, Takeda Y, Kumanogoh A, Okuda M.
  Sci Rep. 2024 Oct 18;14(1):24429.
• Neoself-antigens are the primary target for autoreactive T cells in human lupus.
  Mori S, Kohyama M, Yasumizu Y, Tada A, Tanzawa K, Shishido T, Kishida K, Jin H, Nishide M, Kawada S, Motooka D, Okuzaki D, Naito R, Nakai W, Kanda T, Murata T, Terao C, Ohmura K, Arase N, Kurosaki T, Fujimoto M, Suenaga T, Kumanogoh A, Sakaguchi S, Ogawa Y, Arase H.
  Cell. 2024 Oct 17;187(21):6071-6087.e20.
• Safety, pharmacokinetics, biomarker response and efficacy of E6742: a dual antagonist of Toll-like receptors 7 and 8, in a first in patient, randomised, double-blind, phase I/II study in systemic lupus erythematosus.
  Tanaka Y, Kumanogoh A, Atsumi T, Ishii T, Tago F, Aoki M, Yamamuro S, Akira S.
  RMD Open. 2024 Sep 17;10(3):e004701.
• Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs.
  Nakanishi Y, Izumi M, Matsushita H, Koyama Y, Diez D, Takamatsu H, Koyama S, Nishide M, Naito M, Mizuno Y, Yamaguchi Y, Mae T, Noda Y, Nakaya K, Nojima S, Sugihara F, Okuzaki D, Ikawa M, Shimada S, Kang S, Kumanogoh A.
  Neuron. 2024 Sep 4;112(17):2955-2972.e9.
• PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination.
  Franzolin G, Brundu S, Cojocaru CF, Curatolo A, Ponzo M, Mastrantonio R, Mihara E, Kumanogoh A, Suga H, Takagi J, Tamagnone L, Giraudo E.
  Cancer Immunol Res. 2024 Sep 3;12(9):1286-1301.
• Risk Stratification According to Baseline and Early Change in Neutrophil-to-Lymphocyte Ratio in Advanced Non-Small Cell Lung Cancer Treated with Chemoimmunotherapy: A Multicenter Real-World Study.
  Matsumoto K, Yamamoto Y, Shiroyama T, Kuge T, Mori M, Tamiya M, Kinehara Y, Tamiya A, Suzuki H, Tobita S, Ueno K, Niki T, Nagatomo I, Takeda Y, Kumanogoh A.
  Target Oncol. 2024 Sep;19(5):757-767.
• Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues.
  Tomofuji Y, Edahiro R, Sonehara K, Shirai Y, Kock KH, Wang QS, Namba S, Moody J, Ando Y, Suzuki A, Yata T, Ogawa K, Naito T, Namkoong H, Xuan Lin QX, Buyamin EV, Tan LM, Sonthalia R, Han KY, Tanaka H, Lee H; Asian Immune Diversity Atlas (AIDA) Network; Japan COVID-19 Task Force; Biobank Japan Project; Okuno T, Liu B, Matsuda K, Fukunaga K, Mochizuki H, Park WY, Yamamoto K, Hon CC, Shin JW, Prabhakar S, Kumanogoh A, Okada Y.
  Cell Genom. 2024 Aug 14;4(8):100625.
• CD98 heavy chain protein is overexpressed in non-small cell lung cancer and is a potential target for CAR T-cell therapy.
  Yaga M, Hasegawa K, Ikeda S, Matsubara M, Hiroshima T, Kimura T, Shirai Y, Tansri W, Uehara H, Tachikawa M, Okairi Y, Sone M, Mori H, Kogue Y, Akamine H, Okuzaki D, Kawagishi K, Kawanaka S, Yamato H, Takeuchi Y, Okura E, Kanzaki R, Okami J, Nakamichi I, Nakane S, Kobayashi A, Iwazawa T, Tokunaga T, Yokouchi H, Yano Y, Uchida J, Mori M, Komuta K, Tachi T, Kuroda H, Kijima N, Kishima H, Ichii M, Futami S, Naito Y, Shiroyama T, Miyake K, Koyama S, Hirata H, Takeda Y, Funaki S, Shintani Y, Kumanogoh A, Hosen N.
  Sci Rep. 2024 Aug 2;14(1):17917.
• Heating of the neck or elbows alleviates Raynaud's phenomenon but has different effects on different types of patients with systemic sclerosis.
  Shima Y, Watanabe A, Inoue N, Maruyama T, Kunitomo E, Kumanogoh A.
  Mod Rheumatol. 2024 Jul 6;34(4):750-755.
• SFTPB in serum extracellular vesicles as a biomarker of progressive pulmonary fibrosis.
  Enomoto T, Shirai Y, Takeda Y, Edahiro R, Shichino S, Nakayama M, Takahashi-Itoh M, Noda Y, Adachi Y, Kawasaki T, Koba T, Futami Y, Yaga M, Hosono Y, Yoshimura H, Amiya S, Hara R, Yamamoto M, Nakatsubo D, Suga Y, Naito M, Masuhiro K, Hirata H, Iwahori K, Nagatomo I, Miyake K, Koyama S, Fukushima K, Shiroyama T, Naito Y, Futami S, Natsume-Kitatani Y, Nojima S, Yanagawa M, Shintani Y, Nogami-Itoh M, Mizuguchi K, Adachi J, Tomonaga T, Inoue Y, Kumanogoh A.
  JCI Insight. 2024 Jun 10;9(11):e177937.
• Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology.
  Yoshimura H, Takeda Y, Shirai Y, Yamamoto M, Nakatsubo D, Amiya S, Enomoto T, Hara R, Adachi Y, Edahiro R, Yaga M, Masuhiro K, Koba T, Itoh-Takahashi M, Nakayama M, Takata S, Hosono Y, Obata S, Nishide M, Hata A, Yanagawa M, Namba S, Iwata M, Hamano M, Hirata H, Koyama S, Iwahori K, Nagatomo I, Suga Y, Miyake K, Shiroyama T, Fukushima K, Futami S, Naito Y, Kawasaki T, Mizuguchi K, Kawashima Y, Yamanishi Y, Adachi J, Nogami-Itoh M, Ueki S, Kumanogoh A.
  J Allergy Clin Immunol. 2024 May;153(5):1268-1281.
• Tetracyclines enhance antitumor T-cell immunity via the Zap70 signaling pathway.
  Tone M, Iwahori K, Hirata M, Ueyama A, Tani A, Haruta JI, Takeda Y, Shintani Y, Kumanogoh A, Wada H.
  J Immunother Cancer. 2024 Apr 15;12(4):e008334.
• 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a partial STING agonist, competes for human STING activation.
  Temizoz B, Shibahara T, Hioki K, Hayashi T, Kobiyama K, Lee MSJ, Surucu N, Sag E, Kumanogoh A, Yamamoto M, Gursel M, Ozen S, Kuroda E, Coban C, Ishii KJ.
  Front Immunol. 2024 Mar 12;15:1353336.
• Single-cell transcriptome landscape of circulating CD4⁺ T cell populations in autoimmune diseases.
  Yasumizu Y, Takeuchi D, Morimoto R, Takeshima Y, Okuno T, Kinoshita M, Morita T, Kato Y, Wang M, Motooka D, Okuzaki D, Nakamura Y, Mikami N, Arai M, Zhang X, Kumanogoh A, Mochizuki H, Ohkura N, Sakaguchi S.
  Cell Genom. 2024 Feb 14;4(2):100473.
• Sema6D forward signaling impairs T cell activation and proliferation in head and neck cancer.
  Hirai T, Naito Y, Koyama S, Nakanishi Y, Masuhiro K, Izumi M, Kuge T, Naito M, Mizuno Y, Yamaguchi Y, Kang S, Yaga M, Futami Y, Nojima S, Nishide M, Morita T, Kato Y, Tsuda T, Takemoto N, Kinugasa-Katayama Y, Aoshi T, Villa JK, Yamashita K, Enokida T, Hoshi Y, Matsuura K, Tahara M, Takamatsu H, Takeda Y, Inohara H, Kumanogoh A.
  JCI Insight. 2024 Feb 8;9(3):e166349.
• Balloon Dilatation for Bronchoscope Delivery (BDBD) in a Swine Model: A Novel Technique for Ultra-Peripheral Lung Field Access and Accurate Biopsy.
  Miyake K, Shiroyama T, Satoh S, Adachi Y, Ohira K, Abe Y, Takata S, Masuhiro K, Naito Y, Hirata H, Nagatomo I, Takeda Y, Kumanogoh A.
  Respiration. 2024 Feb 5. doi: 10.1159/000536666.
• GWAS for systemic sclerosis identifies six novel susceptibility loci including one in the Fcγ receptor region.
  Ishikawa Y, Tanaka N, Asano Y, Kodera M, Shirai Y, Akahoshi M, Hasegawa M, Matsushita T, Saito K, Motegi SI, Yoshifuji H, Yoshizaki A, Kohmoto T, Takagi K, Oka A, Kanda M, Tanaka Y, Ito Y, Nakano K, Kasamatsu H, Utsunomiya A, Sekiguchi A, Niiro H, Jinnin M, Makino K, Makino T, Ihn H, Yamamoto M, Suzuki C, Takahashi H, Nishida E, Morita A, Yamamoto T, Fujimoto M, Kondo Y, Goto D, Sumida T, Ayuzawa N, Yanagida H, Horita T, Atsumi T, Endo H, Shima Y, Kumanogoh A, Hirata J, Otomo N, Suetsugu H, Koike Y, Tomizuka K, Yoshino S, Liu X, Ito S, Hikino K, Suzuki A, Momozawa Y, Ikegawa S, Tanaka Y, Ishikawa O, Takehara K, Torii T, Sato S, Okada Y, Mimori T, Matsuda F, Matsuda K, Amariuta T, Imoto I, Matsuo K, Kuwana M, Kawaguchi Y, Ohmura K, Terao C.
  Nat Commun. 2024 Jan 31;15(1):319.
• Cancer-associated SNRPD3 mutation confers resistance to hypoxia, which is attenuated by DRP1 inhibition.
  Satoh S, Miyake K, Adachi Y, Masuhiro K, Futami S, Naito Y, Shiroyama T, Koyama S, Yamaguchi Y, Konaka H, Takamatsu H, Okuzaki D, Nagatomo I, Takeda Y, Kumanogoh A.
  Biochem Biophys Res Commun. 2024 Feb 12;696:149511.
• Idiopathic pulmonary fibrosis-specific Bayesian network integrating extracellular vesicle proteome and clinical information.
  Tomoto M, Mineharu Y, Sato N, Tamada Y, Nogami-Itoh M, Kuroda M, Adachi J, Takeda Y, Mizuguchi K, Kumanogoh A, Natsume-Kitatani Y, Okuno Y.
  Sci Rep. 2024 Jan 15;14(1):1315.
• Efficacy against Lung Cancer Is Augmented by Combining Aberrantly N-Glycosylated T Cells with a Chimeric Antigen Receptor Targeting Fragile X Mental Retardation 1 Neighbor.
  Toyofuku T, Ishikawa T, Nojima S, Kumanogoh A.
  J Immunol. 2024 Mar 1;212(5):917-927.
• Real-world outcomes of nivolumab plus ipilimumab and pembrolizumab with platinum-based chemotherapy in advanced non-small cell lung cancer: a multicenter retrospective comparative study.
  Matsumoto K, Shiroyama T, Tamiya M, Minami T, Kinehara Y, Tamiya A, Suga Y, Kuge T, Mori M, Suzuki H, Tobita S, Ueno K, Namba Y, Tetsumoto S, Niki T, Morimura O, Osa A, Nishino K, Nagatomo I, Takeda Y, Kijima T, Kumanogoh A.
  Cancer Immunol Immunother. 2024 Jan 4;73(1):4.

2023年

• Pneumonitis During Durvalumab Consolidation Therapy Affects Survival in Stage III NSCLC.
  Kinehara Y, Shiroyama T, Tamiya A, Tamiya M, Minami S, Kanazu M, Morimura O, Niki T, Tetsumoto S, Taniguchi Y, Kuge T, Nishino K, Nagatomo I, Kumanogoh A, Tachibana I.
  JTO Clin Res Rep. 2023 Oct 12;4(11):100586.
• Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population.
  Tomofuji Y, Kishikawa T, Sonehara K, Maeda Y, Ogawa K, Kawabata S, Oguro-Igashira E, Okuno T, Nii T, Kinoshita M, Takagaki M, Yamamoto K, Arase N, Yagita-Sakamaki M, Hosokawa A, Motooka D, Matsumoto Y, Matsuoka H, Yoshimura M, Ohshima S, Nakamura S, Fujimoto M, Inohara H, Kishima H, Mochizuki H, Takeda K, Kumanogoh A, Okada Y.
  Cell Rep. 2023 Oct 30: 2023.113324.
• Estimating gene-level false discovery probability improves eQTL statistical fine-mapping precision.
  Wang QS, Edahiro R, Namkoong H, Hasegawa T, Shirai Y, Sonehara K; Japan COVID-19 Task Force; Kumanogoh A, Ishii M, Koike R, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Okada Y.
  NAR Genom Bioinform. 2023 Oct 30;5(4):lqad090.
• Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis.
  Nishide M, Nishimura K, Matsushita H, Edahiro R, Inukai S, Shimagami H, Kawada S, Kato Y, Kawasaki T, Tsujimoto K, Kamon H, Omiya R, Okada Y, Hattori K, Narazaki M, Kumanogoh A.Nat Commun. 2023 Oct 11;14(1):5789
• Automatic evaluation of atlantoaxial subluxation in rheumatoid arthritis by a deep learning model.
  Okita Y, Hirano T, Wang B, Nakashima Y, Minoda S, Nagahara H, Kumanogoh A.Arthritis Res Ther. 2023 Sep 25;25(1):181.
• Heating of the neck or elbows alleviates Raynaud's phenomenon but has different effects on different types of patients with systemic sclerosis.
  Shima Y, Watanabe A, Inoue N, Maruyama T, Kunitomo E, Kumanogoh A.
  Mod Rheumatol. 2023 Sep 14:road091.
• Secretion of mitochondrial DNA via exosomes promotes inflammation in Behçet's syndrome.
  Konaka H, Kato Y, Hirano T, Tsujimoto K, Park J, Koba T, Aoki W, Matsuzaki Y, Taki M, Koyama S, Itotagawa E, Jo T, Hirayama T, Kawai T, Ishii KJ, Ueda M, Yamaguchi S, Akira S, Morita T, Maeda Y, Nishide M, Nishida S, Shima Y, Narazaki M, Takamatsu H, Kumanogoh A.
  EMBO J. 2023 Oct 16;42(20):e112573.
• A randomized phase 2 study on demeclocycline in patients with mild-to-moderate COVID-19.
  Iwahori K, Nii T, Yamaguchi N, Kawasaki T, Okamura S, Hashimoto K, Matsuki T, Tsujino K, Miki K, Osa A, Goya S, Abe K, Mori M, Takeda Y, Yamada T, Kida H, Kumanogoh A.
  Sci Rep. 2023 Aug 23;13(1):13809.
• Comparing the MiniBox™ and the Chestac-8900^® for pulmonary function testing.
  Matsuki T, Yanagi H, Koba T, Aso H, Sakaguchi S, Ito S, Kouyama K, Furuta K, Miyazaki A, Sumitani H, Yokoyama M, Miyamoto S, Fukai M, Hashimoto K, Nii T, Hashimoto H, Fukushima K, Tsujino K, Miki K, Kida H, Kumanogoh A.
  Int J Tuberc Lung Dis. 2023 Sep 1;27(9):709-711.
• Drug retention of biologics and Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study.
  Ebina K, Etani Y, Maeda Y, Okita Y, Hirao M, Yamamoto W, Hashimoto M, Murata K, Hara R, Nagai K, Hiramatsu Y, Son Y, Amuro H, Fujii T, Okano T, Ueda Y, Katayama M, Okano T, Tachibana S, Hayashi S, Kumanogoh A, Okada S, Nakata K.
  RMD Open. 2023 Aug;9(3):e003160.
• Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity.
  Mitsui Y, Suzuki T, Kuniyoshi K, Inamo J, Yamaguchi K, Komuro M, Watanabe J, Edamoto M, Li S, Kouno T, Oba S, Hosoya T, Masuhiro K, Naito Y, Koyama S, Sakaguchi N, Standley DM, Shin JW, Akira S, Yasuda S, Miyazaki Y, Kochi Y, Kumanogoh A, Okamoto T, Satoh T.
  Immunity. 2023 Aug 8;56(8):1939-1954.e12.
• A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth.
  Miyake K, Costa Cruz PH, Nagatomo I, Kato Y, Motooka D, Satoh S, Adachi Y, Takeda Y, Kawahara Y, Kumanogoh A.
  Cell Rep. 2023 Jul 25;42(7):112688.
• Single-cell Raman microscopy with machine learning highlights distinct biochemical features of neutrophil extracellular traps and necrosis.
  Lelliott PM, Hobro AJ, Pavillon N, Nishide M, Okita Y, Mizuno Y, Obata S, Nameki S, Yoshimura H, Kumanogoh A, Smith NI.
  Sci Rep. 2023 Jun 21;13(1):10093.
• T cell immunity in interstitial lung disease with non-small cell lung cancer patients.
  Isono T, Iwahori K, Yanagawa M, Yamamoto Y, Tone M, Haruna M, Hirata M, Fukui E, Kimura T, Kanou T, Ose N, Funaki S, Takeda Y, Morii E, Kumanogoh A, Shintani Y, Wada H.
  Lung Cancer. 2023 Aug;182:107278.
• Impact of Lymphopenia Recovery After Chemoradiotherapy on Durvalumab Consolidation Therapy in Stage III NSCLC.
  Kuge T, Shiroyama T, Tamiya A, Tamiya M, Kanazu M, Kinehara Y, Tanaka T, Morimura O, Taniguchi Y, Niki T, Tetsumoto S, Hayashi K, Nishino K, Nagatomo I, Kumanogoh A.
  JTO Clin Res Rep. 2023 Mar 23;4(5):100505.
• Impact of minocycline on outcomes of EGFR-mutant non-small cell lung cancer patients treated with EGFR-TKIs.
  Tone M, Iwahori K, Shiroyama T, Futami S, Naito Y, Fukushima K, Miyake K, Koyama S, Hirata H, Nagatomo I, Wada H, Takeda Y, Kumanogoh A.
  Sci Rep. 2023 May 23;13(1):8313.
• Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8⁺ T cell cytotoxicity and proliferation.
  Naito Y, Koyama S, Masuhiro K, Hirai T, Uenami T, Inoue T, Osa A, Machiyama H, Watanabe G, Sax N, Villa J, Kinugasa-Katayama Y, Nojima S, Yaga M, Hosono Y, Okuzaki D, Satoh S, Tsuda T, Nakanishi Y, Suga Y, Morita T, Fukushima K, Nishide M, Shiroyama T, Miyake K, Iwahori K, Hirata H, Nagatomo I, Yano Y, Tamiya M, Kumagai T, Takemoto N, Inohara H, Yamasaki S, Yamashita K, Aoshi T, Akbay EA, Hosen N, Shintani Y, Takamatsu H, Mori M, Takeda Y, Kumanogoh A.
  Sci Adv. 2023 May 19;9(20):eade0718.
• Reconstruction of the personal information from human genome reads in gut metagenome sequencing data.
  Tomofuji Y, Sonehara K, Kishikawa T, Maeda Y, Ogawa K, Kawabata S, Nii T, Okuno T, Oguro-Igashira E, Kinoshita M, Takagaki M, Yamamoto K, Kurakawa T, Yagita-Sakamaki M, Hosokawa A, Motooka D, Matsumoto Y, Matsuoka H, Yoshimura M, Ohshima S, Nakamura S, Inohara H, Kishima H, Mochizuki H, Takeda K, Kumanogoh A, Okada Y.
  Nat Microbiol. 2023 Jun;8(6):1079-1094.
• Impact of respiratory bacterial infections on mortality in Japanese patients with COVID-19: a retrospective cohort study.
  Nakagawara K, Kamata H, Chubachi S, Namkoong H, Tanaka H, Lee H, Otake S, Fukushima T, Kusumoto T, Morita A, Azekawa S, Watase M, Asakura T, Masaki K, Ishii M, Endo A, Koike R, Ishikura H, Takata T, Matsushita Y, Harada N, Kokutou H, Yoshiyama T, Kataoka K, Mutoh Y, Miyawaki M, Ueda S, Ono H, Ono T, Shoko T, Muranaka H, Kawamura K, Mori N, Mochimaru T, Fukui M, Chihara Y, Nagasaki Y, Okamoto M, Amishima M, Odani T, Tani M, Nishi K, Shirai Y, Edahiro R, Ando A, Hashimoto N, Ogura S, Kitagawa Y, Kita T, Kagaya T, Kimura Y, Miyazawa N, Tsuchida T, Fujitani S, Murakami K, Sano H, Sato Y, Tanino Y, Otsuki R, Mashimo S, Kuramochi M, Hosoda Y, Hasegawa Y, Ueda T, Takaku Y, Ishiguro T, Fujiwara A, Kuwahara N, Kitamura H, Hagiwara E, Nakamori Y, Saito F, Kono Y, Abe S, Ishii T, Ohba T, Kusaka Y, Watanabe H, Masuda M, Watanabe H, Kimizuka Y, Kawana A, Kasamatsu Y, Hashimoto S, Okada Y, Takano T, Katayama K, Ai M, Kumanogoh A, Sato T, Tokunaga K, Imoto S, Kitagawa Y, Kimura A, Miyano S, Hasegawa N, Ogawa S, Kanai T, Fukunaga K; Japan COVID-19 Task Force.
  BMC Pulm Med. 2023 Apr 26;23(1):146.
• Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity.
  Edahiro R, Shirai Y, Takeshima Y, Sakakibara S, Yamaguchi Y, Murakami T, Morita T, Kato Y, Liu YC, Motooka D, Naito Y, Takuwa A, Sugihara F, Tanaka K, Wing JB, Sonehara K, Tomofuji Y; Japan COVID-19 Task Force; Namkoong H, Tanaka H, Lee H, Fukunaga K, Hirata H, Takeda Y, Okuzaki D, Kumanogoh A, Okada Y.
  Nat Genet. 2023 May;55(5):753-767.
• Identifying phenotypes in interstitial lung disease using group-based trajectory modelling.
  Takata S, Komukai S, Hoshino T, Tabuchi H, Masuhiro K, Yaga M, Shirai Y, Mitsui Y, Abe Y, Kuge T, Fukushima K, Kida H, Kumanogoh A.
  Int J Tuberc Lung Dis. 2023 Apr 1;27(4):332-334.
• Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex.
  Shirai T, Nakai A, Ando E, Fujimoto J, Leach S, Arimori T, Higo D, van Eerden FJ, Tulyeu J, Liu YC, Okuzaki D, Murayama MA, Miyata H, Nunomura K, Lin B, Tani A, Kumanogoh A, Ikawa M, Wing JB, Standley DM, Takagi J, Suzuki K.
  Sci Immunol. 2023 Mar 31;8(81):eadc9324.
• Gut dysbiosis is associated with aortic aneurysm formation and progression in Takayasu arteritis.
  Manabe Y, Ishibashi T, Asano R, Tonomura S, Maeda Y, Motooka D, Ueda J, Yanagawa M, Edamoto-Taira Y, Chikaishi-Kirino T, Masaki T, Inagaki T, Nakamura S, Katada Y, Okazawa M, Narazaki M, Ogo T, Kumanogoh A, Nakaoka Y.
  Arthritis Res Ther. 2023 Mar 24;25(1):46.
• Food additive succinate exacerbates experimental autoimmune encephalomyelitis accompanied by increased IL-1β production.
  Sugiyama Y, Takata K, Kinoshita M, Motooka D, Shiraishi N, Kihara K, Murata H, Beppu S, Koda T, Yamashita K, Namba A, Fujimoto K, Kumanogoh A, Okuno T, Mochizuki H.
  Biochem Biophys Res Commun. 2023 May 14;656:97-103.
• MGIT-seq for the Identification of Nontuberculous Mycobacteria and Drug Resistance: a Prospective Study.
  Fukushima K, Matsumoto Y, Matsuki T, Saito H, Motooka D, Komukai S, Fukui E, Yamuchi J, Nitta T, Niitsu T, Abe Y, Nabeshima H, Nagahama Y, Nii T, Tsujino K, Miki K, Kitada S, Kumanogoh A, Akira S, Nakamura S, Kida H.
  J Clin Microbiol. 2023 Apr 20;61(4):e0162622.
• Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease.
  Shimizu T, Schutt CR, Izumi Y, Tomiyasu N, Omahdi Z, Kano K, Takamatsu H, Aoki J, Bamba T, Kumanogoh A, Takao M, Yamasaki S.
  Immunity. 2023 Feb 14;56(2):307-319.
• Real-world impact of antifibrotics on prognosis in patients with progressive fibrosing interstitial lung disease.
  Niitsu T, Fukushima K, Komukai S, Takata S, Abe Y, Nii T, Kuge T, Iwakoshi S, Shiroyama T, Miyake K, Tujino K, Tanizaki S, Iwahori K, Hirata H, Miki K, Yanagawa M, Takeuchi N, Takeda Y, Kida H, Kumanogoh A.
  RMD Open. 2023 Jan;9(1):e002667.
• Diagnostic significance of secondary bacteremia in patients with COVID-19.
  Nakagawara K, Kamata H, Chubachi S, Namkoong H, Tanaka H, Lee H, Otake S, Fukushima T, Kusumoto T, Morita A, Azekawa S, Watase M, Asakura T, Masaki K, Ishii M, Endo A, Koike R, Ishikura H, Takata T, Matsushita Y, Harada N, Kokutou H, Yoshiyama T, Kataoka K, Mutoh Y, Miyawaki M, Ueda S, Ono H, Ono T, Shoko T, Muranaka H, Kawamura K, Mori N, Mochimaru T, Fukui M, Chihara Y, Nagasaki Y, Okamoto M, Amishima M, Odani T, Tani M, Nishi K, Shirai Y, Edahiro R, Ando A, Hashimoto N, Ogura S, Kitagawa Y, Kita T, Kagaya T, Kimura Y, Miyazawa N, Tsuchida T, Fujitani S, Murakami K, Sano H, Sato Y, Tanino Y, Otsuki R, Mashimo S, Kuramochi M, Hosoda Y, Hasegawa Y, Ueda T, Takaku Y, Ishiguro T, Fujiwara A, Kuwahara N, Kitamura H, Hagiwara E, Nakamori Y, Saito F, Kono Y, Abe S, Ishii T, Ohba T, Kusaka Y, Watanabe H, Masuda M, Watanabe H, Kimizuka Y, Kawana A, Kasamatsu Y, Hashimoto S, Okada Y, Takano T, Katayama K, Ai M, Kumanogoh A, Sato T, Tokunaga K, Imoto S, Kitagawa Y, Kimura A, Miyano S, Hasegawa N, Ogawa S, Kanai T, Fukunaga K; Japan COVID-19 Task Force.
  J Infect Chemother. 2023 Jan 20:S1341-321X(23)00014-4.
• Virtual fluoroscopic preprocedural planning using Ziostation2 for transbronchial biopsy: A prospective self-controlled study.
  Abe Y, Miyake K, Shiroyama T, Hirata H, Nagatomo I, Takeda Y, Kumanogoh A.
  Respir Investig. 2023 Mar;61(2):157-163.
• WT1 Trio Peptide-Based Cancer Vaccine for Rare Cancers Expressing Shared Target WT1.
  Oji Y, Kagawa N, Arita H, Naka N, Hamada KI, Outani H, Shintani Y, Takeda Y, Morii E, Shimazu K, Suzuki M, Nishida S, Nakata J, Tsuboi A, Iwai M, Hayashi S, Imanishi R, Ikejima S, Kanegae M, Iwamoto M, Ikeda M, Yagi K, Shimokado H, Nakajima H, Hasegawa K, Morimoto S, Fujiki F, Nagahara A, Tanemura A, Ueda Y, Mizushima T, Ohmi M, Ishida T, Fujimoto M, Nonomura N, Kimura T, Inohara H, Okada S, Kishima H, Hosen N, Kumanogoh A, Oka Y, Sugiyama H.
  Cancers (Basel). 2023 Jan 6;15(2):393.
• A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients.
  Søndergaard JN, Tulyeu J, Edahiro R, Shirai Y, Yamaguchi Y, Murakami T, Morita T, Kato Y, Hirata H, Takeda Y, Okuzaki D, Sakaguchi S, Kumanogoh A, Okada Y, Wing JB.
  Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217902120.
• Genomic repertoires linked with pathogenic potency of arthritogenic Prevotella copri isolated from the gut of patients with rheumatoid arthritis.
  Nii T, Maeda Y, Motooka D, Naito M, Matsumoto Y, Ogawa T, Oguro-Igashira E, Kishikawa T, Yamashita M, Koizumi S, Kurakawa T, Okumura R, Kayama H, Murakami M, Sakaguchi T, Das B, Nakamura S, Okada Y, Kumanogoh A, Takeda K.
  Ann Rheum Dis. 2023 Jan 10:annrheumdis-2022-222881.
• Persistence of SARS-CoV-2 neutralizing antibodies and anti-Omicron IgG induced by BNT162b2 mRNA vaccine in patients with autoimmune inflammatory rheumatic disease: an explanatory study in Japan.
  Yamaguchi Y, Nameki S, Kato Y, Saita R, Sato T, Nagao S, Murakami T, Yoshimine Y, Amiya S, Morita T, Okita Y, Kawasaki T, Fujimoto J, Ueda Y, Maeda Y, Watanabe A, Takamatsu H, Nishida S, Shima Y, Narazaki M, Kumanogoh A.
  Lancet Reg Health West Pac. 2023 Mar;32:100661.
• The lysosomal Ragulator complex activates NLRP3 inflammasome in vivo via HDAC6.
  Tsujimoto K, Jo T, Nagira D, Konaka H, Park JH, Yoshimura SI, Ninomiya A, Sugihara F, Hirayama T, Itotagawa E, Matsuzaki Y, Takaichi Y, Aoki W, Saita S, Nakamura S, Ballabio A, Nada S, Okada M, Takamatsu H, Kumanogoh A.
  EMBO J. 2023 Jan 4;42(1):e111389.

2022年

• Characteristics of hospitalized patients with COVID-19 during the first to fifth waves of infection: a report from the Japan COVID-19 Task Force.
  Lee H, Chubachi S, Namkoong H, Asakura T, Tanaka H, Otake S, Nakagawara K, Morita A, Fukushima T, Watase M, Kusumoto T, Masaki K, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K; Japan COVID-19 Task Force.
  BMC Infect Dis. 2022 Dec 12;22(1):935.
• Prokaryotic and viral genomes recovered from 787 Japanese gut metagenomes revealed microbial features linked to diets, populations, and diseases.
  Tomofuji Y, Kishikawa T, Maeda Y, Ogawa K, Otake-Kasamoto Y, Kawabata S, Nii T, Okuno T, Oguro-Igashira E, Kinoshita M, Takagaki M, Oyama N, Todo K, Yamamoto K, Sonehara K, Yagita M, Hosokawa A, Motooka D, Matsumoto Y, Matsuoka H, Yoshimura M, Ohshima S, Shinzaki S, Nakamura S, Iijima H, Inohara H, Kishima H, Takehara T, Mochizuki H, Takeda K, Kumanogoh A, Okada Y.
  Cell Genom. 2022 Nov 30;2(12):100219.
• PlexinA1-deficient mice exhibit decreased cell density and augmented oxidative stress in parvalbumin-expressing interneurons in the medial prefrontal cortex.
  Jahan MS, Tsuzuki T, Ito T, Bhuiyan MER, Takahashi I, Takamatsu H, Kumanogoh A, Negishi T, Yukawa K.
  IBRO Neurosci Rep. 2022 Nov 12;13:500-512.
• Next-generation proteomics of serum extracellular vesicles combined with single-cell RNA sequencing identifies MACROH2A1 associated with refractory COVID-19.
  Kawasaki T, Takeda Y, Edahiro R, Shirai Y, Nogami-Itoh M, Matsuki T, Kida H, Enomoto T, Hara R, Noda Y, Adachi Y, Niitsu T, Amiya S, Yamaguchi Y, Murakami T, Kato Y, Morita T, Yoshimura H, Yamamoto M, Nakatsubo D, Miyake K, Shiroyama T, Hirata H, Adachi J, Okada Y, Kumanogoh A.
  Inflamm Regen. 2022 Nov 30;42(1):53.
• Proposal of a novel pipeline involving precise bronchoscopy of distal peripheral pulmonary lesions for genetic testing.
  Takata S, Miyake K, Maeda D, Hatake K, Nagatomo I, Shiroyama T, Masuhiro K, Yaga M, Shirai Y, Mitsui Y, Yachida S, Kumanogoh A.
  Sci Rep. 2022 Nov 17;12(1):19774.
• Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.
  Ishigaki K, Sakaue S, Terao C, Luo Y, Sonehara K, Yamaguchi K, Amariuta T, Too CL, Laufer VA, Scott IC, Viatte S, Takahashi M, Ohmura K, Murasawa A, Hashimoto M, Ito H, Hammoudeh M, Emadi SA, Masri BK, Halabi H, Badsha H, Uthman IW, Wu X, Lin L, Li T, Plant D, Barton A, Orozco G, Verstappen SMM, Bowes J, MacGregor AJ, Honda S, Koido M, Tomizuka K, Kamatani Y, Tanaka H, Tanaka E, Suzuki A, Maeda Y, Yamamoto K, Miyawaki S, Xie G, Zhang J, Amos CI, Keystone E, Wolbink G, van der Horst-Bruinsma I, Cui J, Liao KP, Carroll RJ, Lee HS, Bang SY, Siminovitch KA, de Vries N, Alfredsson L, Rantapää-Dahlqvist S, Karlson EW, Bae SC, Kimberly RP, Edberg JC, Mariette X, Huizinga T, Dieudé P, Schneider M, Kerick M, Denny JC; BioBank Japan Project; Matsuda K, Matsuo K, Mimori T, Matsuda F, Fujio K, Tanaka Y, Kumanogoh A, Traylor M, Lewis CM, Eyre S, Xu H, Saxena R, Arayssi T, Kochi Y, Ikari K, Harigai M, Gregersen PK, Yamamoto K, Louis Bridges S Jr, Padyukov L, Martin J, Klareskog L, Okada Y, Raychaudhuri S.
  Nat Genet. 2022 Nov;54(11):1640-1651.
• Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells.
  Yamaguchi Y, Kato Y, Edahiro R, Søndergaard JN, Murakami T, Amiya S, Nameki S, Yoshimine Y, Morita T, Takeshima Y, Sakakibara S, Naito Y, Motooka D, Liu YC, Shirai Y, Okita Y, Fujimoto J, Hirata H, Takeda Y, Wing JB, Okuzaki D, Okada Y, Kumanogoh A.
  JCI Insight. 2022 Nov 22;7(22):e163347.
• Peripheral T cell cytotoxicity predicts the efficacy of anti-PD-1 therapy for advanced non-small cell lung cancer patients.
  Iwahori K, Uenami T, Yano Y, Ueda T, Tone M, Naito Y, Suga Y, Fukushima K, Shiroyama T, Miyake K, Koyama S, Hirata H, Nagatomo I, Kida H, Mori M, Takeda Y, Kumanogoh A, Wada H.
  Sci Rep. 2022 Oct 19;12(1):17461.
• Impact of treatment line on risks and benefits of immune checkpoint inhibitor in patients with advanced non-small cell lung cancer and interstitial lung disease: a systematic review and meta-analysis of cohort studies.
  Matsumoto K, Shiroyama T, Kuge T, Miyake K, Yamamoto Y, Yoneda M, Yamamoto M, Naito Y, Suga Y, Fukushima K, Koyama S, Iwahori K, Hirata H, Nagatomo I, Takeda Y, Kumanogoh A.
  Transl Lung Cancer Res. 2022 Sep;11(9):1835-1846.
• Heterogeneity of Stroke in Patients with Systemic Lupus Erythematosus.
  Kitano T, Hirano T, Okazaki S, Itotagawa E, Yagita Y, Morita Y, Watanabe A, Takahashi D, Sakaguchi M, Fujiwara H, Todo K, Sasaki T, Kumanogoh A, Mochizuki H.
  Intern Med. 2022;61(20):3045-3052.
• Arm heating to relieve Raynaud's phenomenon in systemic sclerosis: A single-arm multicentre prospective clinical trial.
  Watanabe A, Shima Y, Takahashi H, Akiyama Y, Kodera M, Jinnin M, Azuma N, Ishii K, Kumanogoh A.
  Mod Rheumatol. 2022 Sep 19:roac116.
• SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced by glomeruli in lupus nephritis.
  Itotagawa E, Tomofuji Y, Kato Y, Konaka H, Tsujimoto K, Park J, Nagira D, Hirayama T, Jo T, Hirano T, Morita T, Nishide M, Nishida S, Shima Y, Narazaki M, Okada Y, Takamatsu H, Kumanogoh A.
  Rheumatology (Oxford). 2022 Sep 12:keac528.
• Semaphorin 6D-expressing mesenchymal cells regulate IL-10 production by ILC2s in the lung.
  Naito M, Nakanishi Y, Motomura Y, Takamatsu H, Koyama S, Nishide M, Naito Y, Izumi M, Mizuno Y, Yamaguchi Y, Nojima S, Okuzaki D, Kumanogoh A.
  Life Sci Alliance. 2022 Aug 29;5(11):e202201486.
• The proliferative activity levels of each immune cell population evaluated by mass cytometry are linked to the clinical phenotypes of systemic lupus erythematosus.
  Kajihara A, Morita T, Kato Y, Konaka H, Murakami T, Yamaguchi Y, Koyama S, Takamatsu H, Nishide M, Maeda Y, Watanabe A, Nishida S, Hirano T, Shima Y, Narazaki M, Kumanogoh A.
  Int Immunol. 2023 Jan 21;35(1):27-41.
• The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force.
  Wang QS, Edahiro R, Namkoong H, Hasegawa T, Shirai Y, Sonehara K, Tanaka H, Lee H, Saiki R, Hyugaji T, Shimizu E, Katayama K, Kanai M, Naito T, Sasa N, Yamamoto K, Kato Y, Morita T, Takahashi K, Harada N, Naito T, Hiki M, Matsushita Y, Takagi H, Ichikawa M, Nakamura A, Harada S, Sandhu Y, Kabata H, Masaki K, Kamata H, Ikemura S, Chubachi S, Okamori S, Terai H, Morita A, Asakura T, Sasaki J, Morisaki H, Uwamino Y, Nanki K, Uchida S, Uno S, Nishimura T, Ishiguro T, Isono T, Shibata S, Matsui Y, Hosoda C, Takano K, Nishida T, Kobayashi Y, Takaku Y, Takayanagi N, Ueda S, Tada A, Miyawaki M, Yamamoto M, Yoshida E, Hayashi R, Nagasaka T, Arai S, Kaneko Y, Sasaki K, Tagaya E, Kawana M, Arimura K, Takahashi K, Anzai T, Ito S, Endo A, Uchimura Y, Miyazaki Y, Honda T, Tateishi T, Tohda S, Ichimura N, Sonobe K, Sassa CT, Nakajima J, Nakano Y, Nakajima Y, Anan R, Arai R, Kurihara Y, Harada Y, Nishio K, Ueda T, Azuma M, Saito R, Sado T, Miyazaki Y, Sato R, Haruta Y, Nagasaki T, Yasui Y, Hasegawa Y, Mutoh Y, Kimura T, Sato T, Takei R, Hagimoto S, Noguchi Y, Yamano Y, Sasano H, Ota S, Nakamori Y, Yoshiya K, Saito F, Yoshihara T, Wada D, Iwamura H, Kanayama S, Maruyama S, Yoshiyama T, Ohta K, Kokuto H, Ogata H, Tanaka Y, Arakawa K, Shimoda M, Osawa T, Tateno H, Hase I, Yoshida S, Suzuki S, Kawada M, Horinouchi H, Saito F, Mitamura K, Hagihara M, Ochi J, Uchida T, Baba R, Arai D, Ogura T, Takahashi H, Hagiwara S, Nagao G, Konishi S, Nakachi I, Murakami K, Yamada M, Sugiura H, Sano H, Matsumoto S, Kimura N, Ono Y, Baba H, Suzuki Y, Nakayama S, Masuzawa K, Namba S, Shiroyama T, Noda Y, Niitsu T, Adachi Y, Enomoto T, Amiya S, Hara R, Yamaguchi Y, Murakami T, Kuge T, Matsumoto K, Yamamoto Y, Yamamoto M, Yoneda M, Tomono K, Kato K, Hirata H, Takeda Y, Koh H, Manabe T, Funatsu Y, Ito F, Fukui T, Shinozuka K, Kohashi S, Miyazaki M, Shoko T, Kojima M, Adachi T, Ishikawa M, Takahashi K, Inoue T, Hirano T, Kobayashi K, Takaoka H, Watanabe K, Miyazawa N, Kimura Y, Sado R, Sugimoto H, Kamiya A, Kuwahara N, Fujiwara A, Matsunaga T, Sato Y, Okada T, Hirai Y, Kawashima H, Narita A, Niwa K, Sekikawa Y, Nishi K, Nishitsuji M, Tani M, Suzuki J, Nakatsumi H, Ogura T, Kitamura H, Hagiwara E, Murohashi K, Okabayashi H, Mochimaru T, Nukaga S, Satomi R, Oyamada Y, Mori N, Baba T, Fukui Y, Odate M, Mashimo S, Makino Y, Yagi K, Hashiguchi M, Kagyo J, Shiomi T, Fuke S, Saito H, Tsuchida T, Fujitani S, Takita M, Morikawa D, Yoshida T, Izumo T, Inomata M, Kuse N, Awano N, Tone M, Ito A, Nakamura Y, Hoshino K, Maruyama J, Ishikura H, Takata T, Odani T, Amishima M, Hattori T, Shichinohe Y, Kagaya T, Kita T, Ohta K, Sakagami S, Koshida K, Hayashi K, Shimizu T, Kozu Y, Hiranuma H, Gon Y, Izumi N, Nagata K, Ueda K, Taki R, Hanada S, Kawamura K, Ichikado K, Nishiyama K, Muranaka H, Nakamura K, Hashimoto N, Wakahara K, Koji S, Omote N, Ando A, Kodama N, Kaneyama Y, Maeda S, Kuraki T, Matsumoto T, Yokote K, Nakada TA, Abe R, Oshima T, Shimada T, Harada M, Takahashi T, Ono H, Sakurai T, Shibusawa T, Kimizuka Y, Kawana A, Sano T, Watanabe C, Suematsu R, Sageshima H, Yoshifuji A, Ito K, Takahashi S, Ishioka K, Nakamura M, Masuda M, Wakabayashi A, Watanabe H, Ueda S, Nishikawa M, Chihara Y, Takeuchi M, Onoi K, Shinozuka J, Sueyoshi A, Nagasaki Y, Okamoto M, Ishihara S, Shimo M, Tokunaga Y, Kusaka Y, Ohba T, Isogai S, Ogawa A, Inoue T, Fukuyama S, Eriguchi Y, Yonekawa A, Kan-O K, Matsumoto K, Kanaoka K, Ihara S, Komuta K, Inoue Y, Chiba S, Yamagata K, Hiramatsu Y, Kai H, Asano K, Oguma T, Ito Y, Hashimoto S, Yamasaki M, Kasamatsu Y, Komase Y, Hida N, Tsuburai T, Oyama B, Takada M, Kanda H, Kitagawa Y, Fukuta T, Miyake T, Yoshida S, Ogura S, Abe S, Kono Y, Togashi Y, Takoi H, Kikuchi R, Ogawa S, Ogata T, Ishihara S, Kanehiro A, Ozaki S, Fuchimoto Y, Wada S, Fujimoto N, Nishiyama K, Terashima M, Beppu S, Yoshida K, Narumoto O, Nagai H, Ooshima N, Motegi M, Umeda A, Miyagawa K, Shimada H, Endo M, Ohira Y, Watanabe M, Inoue S, Igarashi A, Sato M, Sagara H, Tanaka A, Ohta S, Kimura T, Shibata Y, Tanino Y, Nikaido T, Minemura H, Sato Y, Yamada Y, Hashino T, Shinoki M, Iwagoe H, Takahashi H, Fujii K, Kishi H, Kanai M, Imamura T, Yamashita T, Yatomi M, Maeno T, Hayashi S, Takahashi M, Kuramochi M, Kamimaki I, Tominaga Y, Ishii T, Utsugi M, Ono A, Tanaka T, Kashiwada T, Fujita K, Saito Y, Seike M, Watanabe H, Matsuse H, Kodaka N, Nakano C, Oshio T, Hirouchi T, Makino S, Egi M, Omae Y, Nannya Y, Ueno T, Takano T, Katayama K, Ai M, Kumanogoh A, Sato T, Hasegawa N, Tokunaga K, Ishii M, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Okada Y.
  Nat Commun. 2022 Aug 22;13(1):4830.
• Add-on Effectiveness of Methotrexate or Iguratimod in Patients with Rheumatoid Arthritis Exhibiting an Inadequate Response to Janus Kinase Inhibitors: The ANSWER Cohort Study.
  Ebina K, Hirano T, Maeda Y, Okita Y, Etani Y, Hirao M, Yamamoto W, Hashimoto M, Murata K, Onishi A, Jinno S, Hara R, Son Y, Amuro H, Kotani T, Shiba H, Katayama M, Yamamoto K, Kumanogoh A, Okada S, Nakata K.
  Mod Rheumatol. 2022 Aug 13:roac092.
• DOCK2 is involved in the host genetics and biology of severe COVID-19.
  Namkoong H, Edahiro R, Takano T, Nishihara H, Shirai Y, Sonehara K, Tanaka H, Azekawa S, Mikami Y, Lee H, Hasegawa T, Okudela K, Okuzaki D, Motooka D, Kanai M, Naito T, Yamamoto K, Wang QS, Saiki R, Ishihara R, Matsubara Y, Hamamoto J, Hayashi H, Yoshimura Y, Tachikawa N, Yanagita E, Hyugaji T, Shimizu E, Katayama K, Kato Y, Morita T, Takahashi K, Harada N, Naito T, Hiki M, Matsushita Y, Takagi H, Aoki R, Nakamura A, Harada S, Sasano H, Kabata H, Masaki K, Kamata H, Ikemura S, Chubachi S, Okamori S, Terai H, Morita A, Asakura T, Sasaki J, Morisaki H, Uwamino Y, Nanki K, Uchida S, Uno S, Nishimura T, Ishiguro T, Isono T, Shibata S, Matsui Y, Hosoda C, Takano K, Nishida T, Kobayashi Y, Takaku Y, Takayanagi N, Ueda S, Tada A, Miyawaki M, Yamamoto M, Yoshida E, Hayashi R, Nagasaka T, Arai S, Kaneko Y, Sasaki K, Tagaya E, Kawana M, Arimura K, Takahashi K, Anzai T, Ito S, Endo A, Uchimura Y, Miyazaki Y, Honda T, Tateishi T, Tohda S, Ichimura N, Sonobe K, Sassa CT, Nakajima J, Nakano Y, Nakajima Y, Anan R, Arai R, Kurihara Y, Harada Y, Nishio K, Ueda T, Azuma M, Saito R, Sado T, Miyazaki Y, Sato R, Haruta Y, Nagasaki T, Yasui Y, Hasegawa Y, Mutoh Y, Kimura T, Sato T, Takei R, Hagimoto S, Noguchi Y, Yamano Y, Sasano H, Ota S, Nakamori Y, Yoshiya K, Saito F, Yoshihara T, Wada D, Iwamura H, Kanayama S, Maruyama S, Yoshiyama T, Ohta K, Kokuto H, Ogata H, Tanaka Y, Arakawa K, Shimoda M, Osawa T, Tateno H, Hase I, Yoshida S, Suzuki S, Kawada M, Horinouchi H, Saito F, Mitamura K, Hagihara M, Ochi J, Uchida T, Baba R, Arai D, Ogura T, Takahashi H, Hagiwara S, Nagao G, Konishi S, Nakachi I, Murakami K, Yamada M, Sugiura H, Sano H, Matsumoto S, Kimura N, Ono Y, Baba H, Suzuki Y, Nakayama S, Masuzawa K, Namba S, Suzuki K, Naito Y, Liu YC, Takuwa A, Sugihara F, Wing JB, Sakakibara S, Hizawa N, Shiroyama T, Miyawaki S, Kawamura Y, Nakayama A, Matsuo H, Maeda Y, Nii T, Noda Y, Niitsu T, Adachi Y, Enomoto T, Amiya S, Hara R, Yamaguchi Y, Murakami T, Kuge T, Matsumoto K, Yamamoto Y, Yamamoto M, Yoneda M, Kishikawa T, Yamada S, Kawabata S, Kijima N, Takagaki M, Sasa N, Ueno Y, Suzuki M, Takemoto N, Eguchi H, Fukusumi T, Imai T, Fukushima M, Kishima H, Inohara H, Tomono K, Kato K, Takahashi M, Matsuda F, Hirata H, Takeda Y, Koh H, Manabe T, Funatsu Y, Ito F, Fukui T, Shinozuka K, Kohashi S, Miyazaki M, Shoko T, Kojima M, Adachi T, Ishikawa M, Takahashi K, Inoue T, Hirano T, Kobayashi K, Takaoka H, Watanabe K, Miyazawa N, Kimura Y, Sado R, Sugimoto H, Kamiya A, Kuwahara N, Fujiwara A, Matsunaga T, Sato Y, Okada T, Hirai Y, Kawashima H, Narita A, Niwa K, Sekikawa Y, Nishi K, Nishitsuji M, Tani M, Suzuki J, Nakatsumi H, Ogura T, Kitamura H, Hagiwara E, Murohashi K, Okabayashi H, Mochimaru T, Nukaga S, Satomi R, Oyamada Y, Mori N, Baba T, Fukui Y, Odate M, Mashimo S, Makino Y, Yagi K, Hashiguchi M, Kagyo J, Shiomi T, Fuke S, Saito H, Tsuchida T, Fujitani S, Takita M, Morikawa D, Yoshida T, Izumo T, Inomata M, Kuse N, Awano N, Tone M, Ito A, Nakamura Y, Hoshino K, Maruyama J, Ishikura H, Takata T, Odani T, Amishima M, Hattori T, Shichinohe Y, Kagaya T, Kita T, Ohta K, Sakagami S, Koshida K, Hayashi K, Shimizu T, Kozu Y, Hiranuma H, Gon Y, Izumi N, Nagata K, Ueda K, Taki R, Hanada S, Kawamura K, Ichikado K, Nishiyama K, Muranaka H, Nakamura K, Hashimoto N, Wakahara K, Sakamoto K, Omote N, Ando A, Kodama N, Kaneyama Y, Maeda S, Kuraki T, Matsumoto T, Yokote K, Nakada TA, Abe R, Oshima T, Shimada T, Harada M, Takahashi T, Ono H, Sakurai T, Shibusawa T, Kimizuka Y, Kawana A, Sano T, Watanabe C, Suematsu R, Sageshima H, Yoshifuji A, Ito K, Takahashi S, Ishioka K, Nakamura M, Masuda M, Wakabayashi A, Watanabe H, Ueda S, Nishikawa M, Chihara Y, Takeuchi M, Onoi K, Shinozuka J, Sueyoshi A, Nagasaki Y, Okamoto M, Ishihara S, Shimo M, Tokunaga Y, Kusaka Y, Ohba T, Isogai S, Ogawa A, Inoue T, Fukuyama S, Eriguchi Y, Yonekawa A, Kan-O K, Matsumoto K, Kanaoka K, Ihara S, Komuta K, Inoue Y, Chiba S, Yamagata K, Hiramatsu Y, Kai H, Asano K, Oguma T, Ito Y, Hashimoto S, Yamasaki M, Kasamatsu Y, Komase Y, Hida N, Tsuburai T, Oyama B, Takada M, Kanda H, Kitagawa Y, Fukuta T, Miyake T, Yoshida S, Ogura S, Abe S, Kono Y, Togashi Y, Takoi H, Kikuchi R, Ogawa S, Ogata T, Ishihara S, Kanehiro A, Ozaki S, Fuchimoto Y, Wada S, Fujimoto N, Nishiyama K, Terashima M, Beppu S, Yoshida K, Narumoto O, Nagai H, Ooshima N, Motegi M, Umeda A, Miyagawa K, Shimada H, Endo M, Ohira Y, Watanabe M, Inoue S, Igarashi A, Sato M, Sagara H, Tanaka A, Ohta S, Kimura T, Shibata Y, Tanino Y, Nikaido T, Minemura H, Sato Y, Yamada Y, Hashino T, Shinoki M, Iwagoe H, Takahashi H, Fujii K, Kishi H, Kanai M, Imamura T, Yamashita T, Yatomi M, Maeno T, Hayashi S, Takahashi M, Kuramochi M, Kamimaki I, Tominaga Y, Ishii T, Utsugi M, Ono A, Tanaka T, Kashiwada T, Fujita K, Saito Y, Seike M, Watanabe H, Matsuse H, Kodaka N, Nakano C, Oshio T, Hirouchi T, Makino S, Egi M; Biobank Japan Project; Omae Y, Nannya Y, Ueno T, Katayama K, Ai M, Fukui Y, Kumanogoh A, Sato T, Hasegawa N, Tokunaga K, Ishii M, Koike R, Kitagawa Y, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K, Okada Y.
  Nature. 2022 Sep;609(7928):754-760.
• Lateral Decubitus Position Enables Further Advancement of the Bronchoscope into the Lung Periphery.
  Miyake K, Shiroyama T, Hirata H, Nagatomo I, Takeda Y, Kumanogoh A.
  J Bronchology Interv Pulmonol. 2022 Oct 1;29(4):307-310.
• T Cell-Intrinsic Vitamin A Metabolism and Its Signaling Are Targets for Memory T Cell-Based Cancer Immunotherapy.
  Fujiki F, Morimoto S, Katsuhara A, Okuda A, Ogawa S, Ueda E, Miyazaki M, Isotani A, Ikawa M, Nishida S, Nakajima H, Tsuboi A, Oka Y, Nakata J, Hosen N, Kumanogoh A, Oji Y, Sugiyama H.
  Front Immunol. 2022 Jun 30;13:935465.
• Impact of the Treatment Line on the Risks and Benefits of Immune Checkpoint Inhibitors in Patients With Non-Small Cell Lung Cancer and Interstitial Lung Disease.
  Matsumoto K, Shiroyama T, Yamamoto Y, Miyake K, Takeda Y, Kumanogoh A.
  Chest. 2022 Jul;162(1):e67-e69.
• Respiratory Impedance is Associated with Ventilation and Diffusing Capacity in Patients with Idiopathic Pulmonary Fibrosis Combined with Emphysema.
  Yamamoto Y, Hirata H, Shiroyama T, Kuge T, Matsumoto K, Yoneda M, Yamamoto M, Naito Y, Suga Y, Fukushima K, Miyake K, Koyama S, Iwahori K, Nagatomo I, Takeda Y, Kumanogoh A.
  Int J Chron Obstruct Pulmon Dis. 2022 Jul 1;17:1495-1506.
• CpG ODN (K3)-toll-like receptor 9 agonist-induces Th1-type immune response and enhances cytotoxic activity in advanced lung cancer patients: a phase I study.
  Otsuka T, Nishida S, Shibahara T, Temizoz B, Hamaguchi M, Shiroyama T, Kimura K, Miyake K, Hirata H, Mizuno Y, Yagita M, Manabe Y, Kuroda E, Takeda Y, Kida H, Ishii KJ, Kumanogoh A.
  BMC Cancer. 2022 Jul 7;22(1):744.
• Multi-trait and cross-population genome-wide association studies across autoimmune and allergic diseases identify shared and distinct genetic component.
  Shirai Y, Nakanishi Y, Suzuki A, Konaka H, Nishikawa R, Sonehara K, Namba S, Tanaka H, Masuda T, Yaga M, Satoh S, Izumi M, Mizuno Y, Jo T, Maeda Y, Nii T, Oguro-Igashira E; Biobank Japan Project; Morisaki T, Kamatani Y, Nakayamada S, Nishigori C, Tanaka Y, Takeda Y, Yamamoto K, Kumanogoh A, Okada Y.
  Ann Rheum Dis. 2022 Jun 26;81(9):1301-12.
• Longitudinal alterations of the gut mycobiota and microbiota on COVID-19 severity.
  Maeda Y, Motooka D, Kawasaki T, Oki H, Noda Y, Adachi Y, Niitsu T, Okamoto S, Tanaka K, Fukushima K, Amiya S, Hara R, Oguro-Igashira E, Matsuki T, Hirata H, Takeda Y, Kida H, Kumanogoh A, Nakamura S, Takeda K.
  BMC Infect Dis. 2022 Jun 24;22(1):572.
• Chronic Pulmonary Disease Caused by Tsukamurella toyonakaense.
  Kuge T, Fukushima K, Matsumoto Y, Saito H, Abe Y, Akiba E, Haduki K, Nitta T, Kawano A, Tanaka M, Hattori Y, Kawasaki T, Matsuki T, Shiroyama T, Motooka D, Tsujino K, Miki K, Mori M, Kitada S, Nakamura S, Iida T, Kumanogoh A, Kida H.
  Emerg Infect Dis. 2022 Jul;28(7):1437-1441.
• Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study.
  Dofuku S, Sonehara K, Miyawaki S, Sakaue S, Imai H, Shimizu M, Hongo H, Shinya Y, Ohara K, Teranishi Y, Okano A, Ono H, Nakatomi H, Teraoka A, Yamamoto K, Maeda Y, Nii T, Kishikawa T, Suzuki K, Hirata J, Takahashi M, Matsuda K, Kumanogoh A, Matsuda F, Okada Y, Saito N.
  Transl Stroke Res. 2022 Jun 14. doi: 10.1007/s12975-022-01049-w.
• Leucine-rich a-2 glycoprotein as a potential biomarker of idiopathic multicentric Castleman disease with pulmonary involvement: a single-center case-control study from Japan.
  Takata S, Takeda Y, Hirata H, Shirai Y, Morita T, Futami Y, Naito Y, Masuhiro K, Shiroyama T, Miyake K, Naka T, Kumanogoh A.
  J Thorac Dis. 2022 May;14(5):1332-1341.
• Safety and immunogenicity of a quadrivalent seasonal influenza vaccine adjuvanted with hydroxypropyl-β-cyclodextrin: A phase 1 clinical trial.
  Watanabe A, Nishida S, Burcu T, Shibahara T, Kusakabe T, Kuroda E, Ishii KJ, Kumanogoh A.
  Vaccine. 2022 Jul 29;40(31):4150-4159.
• Duration of SARS-CoV-2 RNA positivity from various specimens and clinical characteristics in patients with COVID-19: a systematic review and meta-analysis.
  Okita Y, Morita T, Kumanogoh A.
  Inflamm Regen. 2022 Jun 1;42(1):16.
• Quantitative evaluation of emphysema for predicting immunotherapy response in patients with advanced non-small-cell lung cancer.
  Noda Y, Shiroyama T, Masuhiro K, Amiya S, Enomoto T, Adachi Y, Hara R, Niitsu T, Naito Y, Miyake K, Koyama S, Hirata H, Nagatomo I, Takeda Y, Kumanogoh A.
  Sci Rep. 2022 May 25;12(1):8881.
• Anti-Myxovirus Resistance Protein-1 Immunoglobulin A Autoantibody in Idiopathic Pulmonary Fibrosis.
  Arai T, Hirose M, Hamano Y, Kagawa T, Murakami A, Kida H, Kumanogoh A, Inoue Y.
  Can Respir J. 2022 Mar 29;2022:1107673.
• Bronchoalveolar lavage fluid reveals factors contributing to the efficacy of PD-1 blockade in lung cancer.
  Masuhiro K, Tamiya M, Fujimoto K, Koyama S, Naito Y, Osa A, Hirai T, Suzuki H, Okamoto N, Shiroyama T, Nishino K, Adachi Y, Nii T, Kinugasa-Katayama Y, Kajihara A, Morita T, Imoto S, Uematsu S, Irie T, Okuzaki D, Aoshi T, Takeda Y, Kumagai T, Hirashima T, Kumanogoh A.
  JCI Insight. 2022 Apr 7:e157915.
• Tetracyclines Enhance Anti-tumor T-Cell Responses Induced by a Bispecific T-Cell Engager.
  Noguchi Y, Yamamoto Y, Iwahori K, Matsumoto M, Hirata M, Okuyama H, Shintani Y, Kumanogoh A, Wada H.
  Biol Pharm Bull. 2022;45(4):429-437.
• The superiority of manual over automated methods in identifying bronchial trees on identical CT images.
  Takata S, Miyake K, Kumanogoh A.
  Sci Rep. 2022 Mar 30;12(1):5416.
• Identification of CD14 and lipopolysaccharide-binding protein as novel biomarkers for sarcoidosis using proteomics of serum extracellular vesicles.
  Futami Y, Takeda Y, Koba T, Narumi R, Nojima Y, Ito M, Nakayama M, Ishida M, Yoshimura H, Naito Y, Fukushima K, Takimoto T, Edahiro R, Matsuki T, Nojima S, Hirata H, Koyama S, Iwahori K, Nagatomo I, Shirai Y, Suga Y, Satoh S, Futami S, Miyake K, Shiroyama T, Inoue Y, Adachi J, Tomonaga T, Ueda K, Kumanogoh A.
  Int Immunol. 2022 Jun 4;34(6):327-340.
• Cell-Free DNA Derived From Neutrophils Triggers Type 1 Interferon Signature in Neuromyelitis Optica Spectrum Disorder.
  Murata H, Kinoshita M, Yasumizu Y, Motooka D, Beppu S, Shiraishi N, Sugiyama Y, Kihara K, Tada S, Koda T, Konaka H, Takamatsu H, Kumanogoh A, Okuno T, Mochizuki H.
  Neurol Neuroimmunol Neuroinflamm. 2022 Feb 24;9(3):e1149.
• Cellular Adhesion Is a Controlling Factor in Neutrophil Extracellular Trap Formation Induced by Anti-Neutrophil Cytoplasmic Antibodies.
  Lelliott PM, Nishide M, Pavillon N, Okita Y, Shibahara T, Mizuno Y, Yoshimura H, Obata S, Kumanogoh A, Smith NI.
  Immunohorizons. 2022 Feb 22;6(2):170-183.
• Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain.
  Hasegawa K, Ikeda S, Yaga M, Watanabe K, Urakawa R, Iehara A, Iwai M, Hashiguchi S, Morimoto S, Fujiki F, Nakajima H, Nakata J, Nishida S, Tsuboi A, Oka Y, Yoshihara S, Manabe M, Ichihara H, Mugitani A, Aoyama Y, Nakao T, Hirose A, Hino M, Ueda S, Takenaka K, Masuko T, Akashi K, Maruno T, Uchiyama S, Takamatsu S, Wada N, Morii E, Nagamori S, Motooka D, Kanai Y, Oji Y, Nakagawa T, Kijima N, Kishima H, Ikeda A, Ogino T, Shintani Y, Kubo T, Mihara E, Yusa K, Sugiyama H, Takagi J, Miyoshi E, Kumanogoh A, Hosen N.
  Sci Transl Med. 2022 Feb 16;14(632):eaax7706.
• Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis.
  Yoshida G, Kawabata T, Takamatsu H, Saita S, Nakamura S, Nishikawa K, Fujiwara M, Enokidani Y, Yamamuro T, Tabata K, Hamasaki M, Ishii M, Kumanogoh A, Yoshimori T.
  Autophagy. 2022 Jan 13:1-10.
• Factors affecting drug retention of Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study.
  Ebina K, Hirano T, Maeda Y, Yamamoto W, Hashimoto M, Murata K, Onishi A, Jinno S, Hara R, Son Y, Amuro H, Takeuchi T, Yoshikawa A, Katayama M, Yamamoto K, Okita Y, Hirao M, Etani Y, Kumanogoh A, Okada S, Nakata K.
  Sci Rep. 2022 Jan 7;12(1):134.

2021年

• Therapeutic efficacy of denosumab for rheumatoid arthritis: a systematic review and meta-analysis.
  Yagita M, Morita T, Kumanogoh A.
  Rheumatol Adv Pract. 2021 Dec 17;5(3):rkab099.
• Genetic architecture of microRNA expression and its link to complex diseases in the Japanese population.
  Sonehara K, Sakaue S, Maeda Y, Hirata J, Kishikawa T, Yamamoto K, Matsuoka H, Yoshimura M, Nii T, Ohshima S, Kumanogoh A, Okada Y.
  Hum Mol Genet. 2021 Dec 17:ddab361.
• Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.
  Arase N, Tsuji H, Takamatsu H, Jin H, Konaka H, Hamaguchi Y, Tonomura K, Kotobuki Y, Ueda-Hayakawa I, Matsuoka S, Hirano T, Yorifuji H, Murota H, Ohmura K, Nakashima R, Sato T, Kumanogoh A, Katayama I, Arase H, Fujimoto M.
  J Autoimmun. 2022 Jan;126:102774.
• Proximal heat stress up-regulates angiopoietin-1 in fingers and reduces the severity of Raynaud's phenomenon in systemic sclerosis: a single-centre pilot study.
  Shima Y, Watanabe A, Inoue N, Maruyama T, Kunitomo E, Hamano K, Kawanishi T, Takasugi M, Kumanogoh A.
  Mod Rheumatol. 2022 Feb 28;32(2):351-357.
• Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease.
  Tomofuji Y, Kishikawa T, Maeda Y, Ogawa K, Nii T, Okuno T, Oguro-Igashira E, Kinoshita M, Yamamoto K, Sonehara K, Yagita M, Hosokawa A, Motooka D, Matsumoto Y, Matsuoka H, Yoshimura M, Ohshima S, Nakamura S, Inohara H, Mochizuki H, Takeda K, Kumanogoh A, Okada Y.
  Ann Rheum Dis. 2022 Feb;81(2):278-288.
• Cellular and Humoral Immune Responses Induced by an HLA Class I-restricted Peptide Cancer Vaccine Targeting WT1 Are Associated With Favorable Clinical Outcomes in Advanced Ovarian Cancer.
  Nishida S, Morimoto S, Oji Y, Morita S, Shirakata T, Enomoto T, Tsuboi A, Ueda Y, Yoshino K, Shouq A, Kanegae M, Ohno S, Fujiki F, Nakajima H, Nakae Y, Nakata J, Hosen N, Kumanogoh A, Oka Y, Kimura T, Sugiyama H.
  J Immunother. 2022 Jan 1;45(1):56-66.
• Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol.
  Nakagawara K, Namkoong H, Terai H, Masaki K, Tanosaki T, Shimamoto K, Lee H, Tanaka H, Okamori S, Kabata H, Chubachi S, Ikemura S, Kamata H, Yasuda H, Kawada I, Ishii M, Ishibashi Y, Harada S, Fujita T, Ito D, Bun S, Tabuchi H, Kanzaki S, Shimizu E, Fukuda K, Yamagami J, Kobayashi K, Hirano T, Inoue T, Kagyo J, Shiomi T, Ohgino K, Sayama K, Otsuka K, Miyao N, Odani T, Oyamada Y, Masuzawa K, Nakayama S, Suzuki Y, Baba R, Nakachi I, Kuwahara N, Ishiguro T, Mashimo S, Minematsu N, Ueda S, Manabe T, Funatsu Y, Koh H, Yoshiyama T, Saito F, Ishioka K, Takahashi S, Nakamura M, Goto A, Harada N, Kusaka Y, Nakano Y, Nishio K, Tateno H, Edahiro R, Takeda Y, Kumanogoh A, Kodama N, Okamoto M, Umeda A, Hagimura K, Sato T, Miyazaki N, Takemura R, Sato Y, Takebayashi T, Nakahara J, Mimura M, Ogawa K, Shimmura S, Negishi K, Tsubota K, Amagai M, Goto R, Ibuka Y, Hasegawa N, Kitagawa Y, Kanai T, Fukunaga K.
  BMJ Open Respir Res. 2021 Nov;8(1):e001015.
• Impact of treatment timing and sequence of immune checkpoint inhibitors and anti-angiogenic agents for advanced non-small cell lung cancer: A systematic review and meta-analysis.
  Matsumoto K, Shiroyama T, Kuge T, Miyake K, Yamamoto Y, Yoneda M, Yamamoto M, Naito Y, Suga Y, Fukushima K, Koyama S, Iwahori K, Hirata H, Nagatomo I, Takeda Y, Kumanogoh A.
  Lung Cancer. 2021 Dec;162:175-184.
• Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape.
  Takeuchi Y, Tanegashima T, Sato E, Irie T, Sai A, Itahashi K, Kumagai S, Tada Y, Togashi Y, Koyama S, Akbay EA, Karasaki T, Kataoka K, Funaki S, Shintani Y, Nagatomo I, Kida H, Ishii G, Miyoshi T, Aokage K, Kakimi K, Ogawa S, Okumura M, Eto M, Kumanogoh A, Tsuboi M, Nishikawa H.
  Sci Immunol. 2021 Nov 12;6(65):eabc6424.
• Longer Prehospitalization and Preintubation Periods in Intubated Non-survivors and ECMO Patients With COVID-19: A Systematic Review and Meta-Analysis.
  Funakoshi K, Morita T, Kumanogoh A.
  Front Med (Lausanne). 2021 Oct 15;8:727101.
• Prolonged corticosteroid therapy and cytomegalovirus infection in patients with severe COVID-19.
  Yamamoto Y, Shiroyama T, Hirata H, Kuge T, Matsumoto K, Yoneda M, Yamamoto M, Uchiyama A, Takeda Y, Kumanogoh A.
  J Med Virol. 2021 Oct 28:10.1002/jmv.27421.
• Rapid attenuation of anti-SARS-CoV-2 antibodies in patients with musculoskeletal diseases in whom intensive immunosuppressive therapies were reinitiated after COVID-19: comment on the article by Curtis et al.
  Okamoto M, Kawada S, Shimagami H, Fujii N, Matsukawa K, Ishikawa N, Kawamoto K, Higa S, Ishida Y, Ogata A, Yamaguchi Y, Morita T, Kato Y, Kumanogoh A.
  Arthritis Rheumatol. 2022 Apr;74(4):726-728.
• Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients.
  Lu X, Hosono Y, Nagae M, Ishizuka S, Ishikawa E, Motooka D, Ozaki Y, Sax N, Maeda Y, Kato Y, Morita T, Shinnakasu R, Inoue T, Onodera T, Matsumura T, Shinkai M, Sato T, Nakamura S, Mori S, Kanda T, Nakayama EE, Shioda T, Kurosaki T, Takeda K, Kumanogoh A, Arase H, Nakagami H, Yamashita K, Takahashi Y, Yamasaki S.
  J Exp Med. 2021 Dec 6;218(12):e20211327.
• Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in Japanese.
  Tomofuji Y, Maeda Y, Oguro-Igashira E, Kishikawa T, Yamamoto K, Sonehara K, Motooka D, Matsumoto Y, Matsuoka H, Yoshimura M, Yagita M, Nii T, Ohshima S, Nakamura S, Inohara H, Takeda K, Kumanogoh A, Okada Y.
  Ann Rheum Dis. 2021 Dec;80(12):1575-1583.
• Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats.
  Ishikura T, Kinoshita M, Shimizu M, Yasumizu Y, Motooka D, Okuzaki D, Yamashita K, Murata H, Beppu S, Koda T, Tada S, Shiraishi N, Sugiyama Y, Miyamoto K, Kusunoki S, Sugimoto T, Kumanogoh A, Okuno T, Mochizuki H.
  J Neuroinflammation. 2021 Aug 21;18(1):181.
• IL-33 Induces Sema4A Expression in Dendritic Cells and Exerts Antitumor Immunity.
  Suga Y, Nagatomo I, Kinehara Y, Koyama S, Okuzaki D, Osa A, Naito Y, Takamatsu H, Nishide M, Nojima S, Ito D, Tsuda T, Nakatani T, Nakanishi Y, Futami Y, Koba T, Satoh S, Hosono Y, Miyake K, Fukushima K, Shiroyama T, Iwahori K, Hirata H, Takeda Y, Kumanogoh A.
  J Immunol. 2021 Sep 1;207(5):1456-1467.
• Distinct difference in tumor-infiltrating immune cells between Wilms' tumor gene 1 peptide vaccine and anti-programmed cell death-1 antibody therapies.
  Yokota C, Nakata J, Takano K, Nakajima H, Hayashibara H, Minagawa H, Chiba Y, Hirayama R, Kijima N, Kinoshita M, Hashii Y, Tsuboi A, Oka Y, Oji Y, Kumanogoh A, Sugiyama H, Kagawa N, Kishima H.
  Neurooncol Adv. 2021 Jun 29;3(1):vdab091.
• Cytomegalovirus infection in critically ill patients with COVID-19.
  Niitsu T, Shiroyama T, Hirata H, Noda Y, Adachi Y, Enomoto T, Hara R, Amiya S, Uchiyama A, Takeda Y, Kumanogoh A.
  J Infect. 2021 Oct;83(4):496-522.
• Mapping the human genetic architecture of COVID-19.
  COVID-19 Host Genetics Initiative.
  Nature. 2021 Dec;600(7889):472-477.
• Loss of FCHSD1 leads to amelioration of chronic obstructive pulmonary disease.
  Kawasaki T, Sugihara F, Fukushima K, Matsuki T, Nabeshima H, Machida T, Mitsui Y, Fujimura S, Sagawa R, Gaheun L, Kuniyoshi K, Tanaka H, Narazaki M, Kumanogoh A, Akira S, Satoh T.
  Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2019167118.
• The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II.
  Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, Konaka H, Morita T, Kato Y, Nishide M, Koyama S, Nada S, Okada M, Takamatsu H, Kumanogoh A.
  Nat Commun. 2021 Jun 7;12(1):3333.
• Effect of Reduced-Dose vs High-Dose Glucocorticoids Added to Rituximab on Remission Induction in ANCA-Associated Vasculitis: A Randomized Clinical Trial.
  Furuta S, Nakagomi D, Kobayashi Y, Hiraguri M, Sugiyama T, Amano K, Umibe T, Kono H, Kurasawa K, Kita Y, Matsumura R, Kaneko Y, Ninagawa K, Hiromura K, Kagami SI, Inaba Y, Hanaoka H, Ikeda K, Nakajima H; LoVAS Collaborators.
  JAMA. 2021 Jun 1;325(21):2178-2187.
• Comparison of efficacy between anti-IL-6 receptor antibody and other biological disease-modifying antirheumatic drugs in the patients with rheumatoid arthritis who have knee joint involvement: the ANSWER cohort, retrospective study.
  Maeda Y, Hirano T, Ebina K, Hara R, Hashimoto M, Yamamoto W, Murakami K, Kotani T, Hata K, Son Y, Amuro H, Onishi A, Jinno S, Katayama M, Kumanogoh A.
  Rheumatol Int. 2021 Jul;41(7):1233-1241.
• Large-scale plasma-metabolome analysis identifies potential biomarkers of psoriasis and its clinical subtypes.
  Kishikawa T, Arase N, Tsuji S, Maeda Y, Nii T, Hirata J, Suzuki K, Yamamoto K, Masuda T, Ogawa K, Ohshima S, Inohara H, Kumanogoh A, Fujimoto M, Okada Y.
  J Dermatol Sci. 2021 May;102(2):78-84.
• Aryl hydrocarbon receptor is essential for the pathogenesis of pulmonary arterial hypertension.
  Masaki T, Okazawa M, Asano R, Inagaki T, Ishibashi T, Yamagishi A, Umeki-Mizushima S, Nishimura M, Manabe Y, Ishibashi-Ueda H, Shirai M, Tsuchimochi H, Pearson JT, Kumanogoh A, Sakata Y, Ogo T, Kishimoto T, Nakaoka Y.
  Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2023899118.
• Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres.
  Koba T, Takeda Y, Narumi R, Shiromizu T, Nojima Y, Ito M, Kuroyama M, Futami Y, Takimoto T, Matsuki T, Edahiro R, Nojima S, Hayama Y, Fukushima K, Hirata H, Koyama S, Iwahori K, Nagatomo I, Suzuki M, Shirai Y, Murakami T, Nakanishi K, Nakatani T, Suga Y, Miyake K, Shiroyama T, Kida H, Sasaki T, Ueda K, Mizuguchi K, Adachi J, Tomonaga T, Kumanogoh A.
  ERJ Open Res. 2021 Mar 22;7(1):00658-2020.
• Greater reductions in blood flow after anti-angiogenic treatment in non-small cell lung cancer patients are associated with shorter progression-free survival.
  Katayama D, Yanagawa M, Matsunaga K, Watabe H, Watabe T, Kato H, Kijima T, Takeda Y, Kumanogoh A, Shimosegawa E, Hatazawa J, Tomiyama N.
  Sci Rep. 2021 Mar 24;11(1):6805.
• Radioligand Assay-Based Detection of Antibodies against SARS-CoV-2 in Hospital Workers Treating Patients with Severe COVID-19 in Japan.
  Matsunaga H, Makino A, Kato Y, Murakami T, Yamaguchi Y, Kumanogoh A, Oba Y, Fujimi S, Honda T, Tomonaga K.
  Viruses. 2021 Feb 23;13(2):347.
• Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis.
  Sakaue S, Yamaguchi E, Inoue Y, Takahashi M, Hirata J, Suzuki K, Ito S, Arai T, Hirose M, Tanino Y, Nikaido T, Ichiwata T, Ohkouchi S, Hirano T, Takada T, Miyawaki S, Dofuku S, Maeda Y, Nii T, Kishikawa T, Ogawa K, Masuda T, Yamamoto K, Sonehara K, Tazawa R, Morimoto K, Takaki M, Konno S, Suzuki M, Tomii K, Nakagawa A, Handa T, Tanizawa K, Ishii H, Ishida M, Kato T, Takeda N, Yokomura K, Matsui T, Watanabe M, Inoue H, Imaizumi K, Goto Y, Kida H, Fujisawa T, Suda T, Yamada T, Satake Y, Ibata H, Hizawa N, Mochizuki H, Kumanogoh A, Matsuda F, Nakata K, Hirota T, Tamari M, Okada Y.
  Nat Commun. 2021 Feb 15;12(1):1032.
• Drug retention of sarilumab, baricitinib, and tofacitinib in patients with rheumatoid arthritis: the ANSWER cohort study.
  Ebina K, Hirano T, Maeda Y, Yamamoto W, Hashimoto M, Murata K, Onishi A, Jinno S, Hara R, Son Y, Amuro H, Takeuchi T, Yoshikawa A, Katayama M, Yamamoto K, Hirao M, Okita Y, Kumanogoh A, Nakata K.
  Clin Rheumatol. 2021 Jul;40(7):2673-2680.
• Predicting recurrence of respiratory failure in critically ill patients with COVID-19: A preliminary study.
  Adachi Y, Shiroyama T, Yamaguchi Y, Murakami T, Hirata H, Amiya S, Niitsu T, Noda Y, Hara R, Enomoto T, Morita T, Kato Y, Uchiyama A, Takeda Y, Kumanogoh A.
  J Infect. 2021 May;82(5):e33-e35.
• Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis.
  Zhu M, Huang Y, Bender ME, Girard L, Kollipara R, Eglenen-Polat B, Naito Y, Savage TK, Huffman KE, Koyama S, Kumanogoh A, Minna JD, Johnson JE, Akbay EA.
  Cancer Res. 2021 Apr 1;81(7):1813-1826.

2020年

• A Metagenome-Wide Association Study of Gut Microbiome in Patients With Multiple Sclerosis Revealed Novel Disease Pathology.
  Kishikawa T, Ogawa K, Motooka D, Hosokawa A, Kinoshita M, Suzuki K, Yamamoto K, Masuda T, Matsumoto Y, Nii T, Maeda Y, Nakamura S, Inohara H, Mochizuki H, Okuno T, Okada Y.
  Front Cell Infect Microbiol. 2020 Dec 11;10:585973.
• Integrative Analysis Reveals Common and Unique Roles of Tetraspanins in Fibrosis and Emphysema.
  Tripathi LP, Itoh MN, Takeda Y, Tsujino K, Kondo Y, Kumanogoh A, Mizuguchi K.
  Front Genet. 2020 Dec 10;11:585998.
• Comparison of the efficacy and safety of biologic agents between elderly-onset and young-onset RA patients: the ANSWER cohort study.
  Jinno S, Onishi A, Dubreuil M, Akashi K, Hashimoto M, Yamamoto W, Murata K, Takeuchi T, Kotani T, Maeda Y, Ebina K, Son Y, Amuro H, Hara R, Katayama M, Saegusa J, Morinobu A.
  Rheumatol Int. 2020 Dec;40(12):1987-1995.
• Oral intake of silica nanoparticles exacerbates intestinal inflammation.
  Ogawa T, Okumura R, Nagano K, Minemura T, Izumi M, Motooka D, Nakamura S, Iida T, Maeda Y, Kumanogoh A, Tsutsumi Y, Takeda K.
  Biochem Biophys Res Commun. 2021 Jan 1;534:540-546.
• Pulmonary metastases of lung adenocarcinoma mimicking COVID-19 pneumonia.
  Shiroyama T, Hirata H, Nagatomo I, Takeda Y, Kumanogoh A.
  J Thorac Dis. 2020 Oct;12(10):6125-6126.
• PlexinA1 deficiency in BALB/cAJ mice leads to excessive self-grooming and reduced prepulse inhibition.
  Jahan MS, Ito T, Ichihashi S, Masuda T, Bhuiyan MER, Takahashi I, Takamatsu H, Kumanogoh A, Tsuzuki T, Negishi T, Yukawa K.
  IBRO Rep. 2020 Oct 22;9:276-289.
• Enhanced immune reaction resulting from co-vaccination of WT1 helper peptide assessed on PET-CT.
  Nakata J, Isohashi K, Morimoto S, Itou R, Kamiya T, Matsuura A, Nakajima H, Fujiki F, Nishida S, Hasii Y, Hasegawa K, Nakatsuka S, Hosen N, Tsuboi A, Oka Y, Kumanogoh A, Shibano M, Munakata S, Oji Y, Hatazawa J, Sugiyama H.
  Medicine (Baltimore). 2020 Sep 25;99(39):e22417.
• Metabolomic analysis of fibrotic mice combined with public RNA-Seq human lung data reveal potential diagnostic biomarker candidates for lung fibrosis.
  Nojima Y, Takeda Y, Maeda Y, Bamba T, Fukusaki E, Itoh MN, Mizuguchi K, Kumanogoh A.
  FEBS Open Bio. 2020 Nov;10(11):2427-2436.
• Increased levels of plasma nucleotides in patients with rheumatoid arthritis.
  Kishikawa T, Maeda Y, Nii T, Arase N, Hirata J, Suzuki K, Yamamoto K, Masuda T, Ogawa K, Tsuji S, Matsushita M, Matsuoka H, Yoshimura M, Tsunoda S, Ohshima S, Narazaki M, Ogata A, Saeki Y, Inohara H, Kumanogoh A, Takeda K, Okada Y.
  Int Immunol. 2021 Jan 28;33(2):119-124.
• Tocilizumab in systemic sclerosis: a randomised, double-blind, placebo-controlled, phase 3 trial.
  Khanna D, Lin CJF, Furst DE, Goldin J, Kim G, Kuwana M, Allanore Y, Matucci-Cerinic M, Distler O, Shima Y, van Laar JM, Spotswood H, Wagner B, Siegel J, Jahreis A, Denton CP; focuSSced investigators.
  Lancet Respir Med. 2020 Oct;8(10):963-974.
• Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity.
  Tanaka S, Ise W, Inoue T, Ito A, Ono C, Shima Y, Sakakibara S, Nakayama M, Fujii K, Miura I, Sharif J, Koseki H, Koni PA, Raman I, Li QZ, Kubo M, Fujiki K, Nakato R, Shirahige K, Araki H, Miura F, Ito T, Kawakami E, Baba Y, Kurosaki T.
  Nat Immunol. 2020 Aug;21(8):950-961.
• Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells.
  Takahashi D, Hoshina N, Kabumoto Y, Maeda Y, Suzuki A, Tanabe H, Isobe J, Yamada T, Muroi K, Yanagisawa Y, Nakamura A, Fujimura Y, Saeki A, Ueda M, Matsumoto R, Asaoka H, Clarke JM, Harada Y, Umemoto E, Komatsu N, Okada T, Takayanagi H, Takeda K, Tomura M, Hase K.
  EBioMedicine. 2020 Aug;58:102913.
• Reader-free ELISPOT assay for immuno-monitoring in peptide-based cancer vaccine immunotherapy.
  Hayashi S, Imanishi R, Adachi M, Ikejima S, Nakata J, Morimoto S, Fujiki F, Nishida S, Tsuboi A, Hosen N, Nakajima H, Hasegawa K, Oka Y, Sugiyama H, Oji Y.
  Biomed Rep. 2020 May;12(5):244-250.
• The family history of rheumatoid arthritis in anti-cyclic citrullinated peptide antibody-positive patient is not a predictor of poor clinical presentation and treatment response with modern classification criteria and treatment strategy: the ANSWER cohort study.
  Murata K, Hashimoto M, Yamamoto W, Son Y, Amuro H, Nagai K, Takeuchi T, Katayama M, Maeda Y, Ebina K, Hara R, Jinno S, Onishi A, Murakami K, Tanaka M, Ito H, Mimori T, Matsuda S.
  Rheumatol Int. 2020 Feb;40(2):217-225.
• Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation.
  Shimizu M, Okuno T, Kinoshita M, Sumi H, Fujimura H, Yamashita K, Sugimoto T, Sakakibara S, Sakakibara K, Koda T, Tada S, Ishikura T, Murata H, Beppu S, Shiraishi N, Sugiyama Y, Nakatsuji Y,Kumanogoh A, Mochizuki H.
  Sci Rep. 2020 Aug 6;10(1):13274.
• Association of the RPA3-UMAD1 locus with interstitial lung diseases complicated with rheumatoid arthritis in Japanese.
  Shirai Y, Honda S, Ikari K, Kanai M, Takeda Y, Kamatani Y, Morisaki T, Tanaka E, Kumanogoh A, Harigai M, Okada Y.
  Ann Rheum Dis. 2020 Oct;79(10):1305-1309.
• Tet DNA demethylase is required for plasma cell differentiation by controlling expression levels of IRF4.
  Fujii K, Tanaka S, Hasegawa T, Narazaki M, Kumanogoh A, Koseki H, Kurosaki T, Ise W.
  Int Immunol. 2020 Sep 30;32(10):683-690.
• Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury.
  Ueno M, Nakamura Y, Nakagawa H, Niehaus JK, Maezawa M, Gu Z, Kumanogoh A, Takebayashi H, Lu QR, Takada M, Yoshida Y.
  Cereb Cortex. 2020 Oct 1;30(11):5702-5716.
• Drug retention of 7 biologics and tofacitinib in biologics-naïve and biologics-switched patients with rheumatoid arthritis: the ANSWER cohort study.
  Ebina K, Hirano T, Maeda Y, Yamamoto W, Hashimoto M, Murata K, Takeuchi T, Shiba H, Son Y, Amuro H, Onishi A, Akashi K, Hara R, Katayama M, Yamamoto K, Kumanogoh A, Hirao M.
  Arthritis Res Ther. 2020 Jun 15;22(1):142.
• Pristane/Hypoxia (PriHx) Mouse as a Novel Model of Pulmonary Hypertension Reflecting Inflammation and Fibrosis.
  Mori H, Ishibashi T, Inagaki T, Okazawa M, Masaki T, Asano R, Manabe Y, Ohta-Ogo K, Narazaki M, Ishibashi-Ueda H, Kumanogoh A, Nakaoka Y.
  Circ J. 2020 Jun 25;84(7):1163-1172.
• The therapeutic efficacy of denosumab for the loss of bone mineral density in glucocorticoid-induced osteoporosis: a meta-analysis.
  Yamaguchi Y, Morita T, Kumanogoh A.
  Rheumatol Adv Pract. 2020 Mar 13;4(1):rkaa008.
• Efficacy of mycophenolate mofetil as a remission induction therapy in antineutrophil cytoplasmic antibody: associated vasculitis-a meta-analysis.
  Kuzuya K, Morita T, Kumanogoh A.
  RMD Open. 2020 Apr;6(1):e001195.
• Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis.
  Fukushima K, Satoh T, Sugihara F, Sato Y, Okamoto T, Mitsui Y, Yoshio S, Li S, Nojima S, Motooka D, Nakamura S, Kida H, Standley DM, Morii E, Kanto T, Yanagita M, Matsuura Y, Nagasawa T,Kumanogoh A, Akira S.
  Immunity. 2020 Mar 17;52(3):542-556.e13.
• Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase.
  Koda T, Namba A, Kinoshita M, Nakatsuji Y, Sugimoto T, Sakakibara K, Tada S, Shimizu M, Yamashita K, Takata K, Ishikura T, Murata S, Beppu S, Kumanogoh A, Mochizuki H, Okuno T.
  J Neuroinflammation. 2020 Mar 13;17(1):82.
• Drug retention of secondary biologics or JAK inhibitors after tocilizumab or abatacept failure as first biologics in patients with rheumatoid arthritis -the ANSWER cohort study.
  Ebina K, Hirano T, Maeda Y, Yamamoto W, Hashimoto M, Murata K, Takeuchi T, Nagai K, Son Y, Amuro H, Onishi A, Jinno S, Hara R, Katayama M, Yamamoto K, Kumanogoh A, Hirao M.
  Clin Rheumatol. 2020 Sep;39(9):2563-2572.
• Immunotherapeutic potential of CD4 and CD8 single-positive T cells in thymic epithelial tumors.
  Yamamoto Y, Iwahori K, Funaki S, Matsumoto M, Hirata M, Yoshida T, Kanzaki R, Kanou T, Ose N, Minami M, Sato E, Kumanogoh A, Shintani Y, Okumura M, Wada H.
  Sci Rep. 2020 Mar 4;10(1):4064.
• Docetaxel Upregulates HMGB1 Levels in Non-small Cell Lung Cancer.
  Haruna M, Hirata M, Iwahori K, Kanazawa T, Yamamoto Y, Goto K, Kawashima A, Morimoto-Okazawa A, Funaki S, Shintani Y, Kumanogoh A, Wada H.
  Biol Pharm Bull. 2020;43(3):399-403.
• Monitoring PD-1-Blocking Antibodies Bound to T Cells Derived from a Drop of Peripheral Blood.
  Naito Y, Osa A, Masuhiro K, Hirai T, Koyama S, Kumanogoh A.
  J Vis Exp. 2020 Feb 5;(156). doi: 10.3791/60608.
• Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis.
  Tsuda T, Nishide M, Maeda Y, Hayama Y, Koyama S, Nojima S, Takamatsu H, Okuzaki D, Morita T, Nakatani T, Kato Y, Nakanishi Y, Futami Y, Suga Y, Naito Y, Konaka H, Satoh S, Naito M, Izumi M, Obata S, Nakatani A, Shikina T, Takeda K, Hayama M, Inohara H, Kumanogoh A.
  J Allergy Clin Immunol. 2020 Mar;145(3):843-854.
• Blockade of N-Glycosylation Promotes Antitumor Immune Response of T Cells.
  Sasawatari S, Okamoto Y, Kumanogoh A, Toyofuku T.
  J Immunol. 2020 Mar 1;204(5):1373-1385.
• Real-Time Monitoring and Detection of Single-Cell Level Cytokine Secretion Using LSPR Technology.
  Zhu C, Luo X, Espulgar WV, Koyama S, Kumanogoh A, Saito M, Takamatsu H, Tamiya E.
  Micromachines (Basel). 2020 Jan 19;11(1): E107.
• A Microfluidic Platform for Single Cell Fluorometric Granzyme B Profiling.
  Briones JC, Espulgar WV, Koyama S, Yoshikawa H, Park J, Naito Y, Kumanogoh A, Tamiya E, Takamatsu H, Saito M.
  Theranostics. 2020 Jan 1;10(1):123-132.
• LRRK2 regulates endoplasmic reticulum-mitochondrial tethering through the PERK-mediated ubiquitination pathway.
  Toyofuku T, Okamoto Y, Ishikawa T, Sasawatari S, Kumanogoh A.
  EMBO J. 2020 Jan 15;39(2):e100875.
• Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population.
  Kishikawa T, Maeda Y, Nii T, Motooka D, Matsumoto Y, Matsushita M, Matsuoka H, Yoshimura M, Kawada S, Teshigawara S, Oguro E, Okita Y, Kawamoto K, Higa S, Hirano T, Narazaki M, Ogata A, Saeki Y, Nakamura S, Inohara H, Kumanogoh A, Takeda K, Okada Y.
  Ann Rheum Dis. 2020 Jan;79(1):103-111.

2019年

• Development and validation of a deep-learning model for scoring of radiographic finger joint destruction in rheumatoid arthritis.
  Hirano T, Nishide M, Nonaka N, Seita J, Ebina K, Sakurada K, Kumanogoh A.
  Rheumatol Adv Pract. 2019 Nov 22;3(2):rkz047.
• Lipid nanoparticles of Type-A CpG D35 suppress tumor growth by changing tumor immune-microenvironment and activate CD8 T cells in mice.
  Munakata L, Tanimoto Y, Osa A, Meng J, Haseda Y, Naito Y, Machiyama H, Kumanogoh A, Omata D, Maruyama K, Yoshioka Y, Okada Y, Koyama S, Suzuki R, Aoshi T.
  J Control Release. 2019 Nov 10;313:106-119.
• Monitoring antibody binding to T cells in a pembrolizumab-treated patient with lung adenocarcinoma on hemodialysis.
  Osa A, Uenami T, Naito Y, Hirata H, Koyama S, Takimoto T, Shiroyama T, Futami S, Nakatsubo S, Sawa N, Yano Y, Nagatomo I, Takeda Y, Mori M, Kida H, Kumanogoh A.
  Thorac Cancer. 2019 Nov;10(11):2183-2187.
• The Outcomes of Induction Chemoradiotherapy Followed by Surgery for Clinical T3-4 Non-Small Cell Lung Cancer.
  Kanzaki R, Ose N, Funaki S, Shintani Y, Minami M, Suzuki O, Kida H, Ogawa K, Kumanogoh A, Okumura M.
  Technol Cancer Res Treat. 2019 Jan 1;18:1533033819871327.
• PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice.
  Hossain MM, Tsuzuki T, Sakakibara K, Imaizumi F, Ikegaya A, Inagaki M, Takahashi I, Ito T, Takamatsu H, Kumanogoh A, Negishi T, Yukawa K.
  PLoS One. 2019 Aug 20;14(8):e0221440.
• Immune adjuvant therapy using Bacillus Calmette-Guérin cell wall skeleton (BCG-CWS) in advanced malignancies: A phase 1 study of safety and immunogenicity assessments.
  Nishida S, Tsuboi A, Tanemura A, Ito T, Nakajima H, Shirakata T, Morimoto S, Fujiki F, Hosen N, Oji Y, Kumanogoh A, Kawase I, Oka Y, Azuma I, Morita S, Sugiyama H.
  Medicine (Baltimore). 2019 Aug;98(33):e16771.
• The therapeutic efficacy of intravenous immunoglobulin in anti-neutrophilic cytoplasmic antibody-associated vasculitis: a meta-analysis.
  Shimizu T, Morita T, Kumanogoh A.
  Rheumatology (Oxford). 2020 May 1;59(5):959-967. 2019 Aug 4. pii: kez311.
• The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors.
  Nakai A, Fujimoto J, Miyata H, Stumm R, Narazaki M, Schulz S, Baba Y, Kumanogoh A, Suzuki K.
  J Exp Med. 2019 Jul 1;216(7):1630-1647.
• Response to: 'Blood plasma versus serum: which is right for sampling circulating membrane microvesicles in human subjects?' by Liu et al.
  Kato Y, Park J, Takamatsu H, Kumanogoh A.
  Ann Rheum Dis. 2019 May 16. pii: annrheumdis-2019-215540.
• Add-on tocilizumab versus conventional treatment for systemic sclerosis, and cytokine analysis to identify an endotype to tocilizumab therapy.
  Shima Y, Kawaguchi Y, Kuwana M.
  Mod Rheumatol. 2019 Jan;29(1):134-139.
• Drug tolerability and reasons for discontinuation of seven biologics in elderly patients with rheumatoid arthritis -The ANSWER cohort study.
  Ebina K, Hashimoto M, Yamamoto W, Hirano T, Hara R, Katayama M, Onishi A, Nagai K, Son Y, Amuro H, Yamamoto K, Maeda Y, Murata K, Jinno S, Takeuchi T, Hirao M, Kumanogoh A, Yoshikawa H.
  PLoS One. 2019 May 8;14(5):e0216624.
• Drug tolerability and reasons for discontinuation of seven biologics in 4466 treatment courses of rheumatoid arthritis-the ANSWER cohort study.
  Ebina K, Hashimoto M, Yamamoto W, Hirano T, Hara R, Katayama M, Onishi A, Nagai K, Son Y, Amuro H, Yamamoto K, Maeda Y, Murata K, Jinno S, Takeuchi T, Hirao M, Kumanogoh A, Yoshikawa H.
  Arthritis Res Ther. 2019 Apr 11;21(1):91
• Transport of cellular misfolded proteins to the cell surface by HLA-B27 free heavy chain.
  Yorifuji H, Arase N, Kohyama M, Hirano T, Suenaga T, Kumanogoh A, Arase H.
  Biochem Biophys Res Commun. 2019 Apr 16;511(4):862-868.
• Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment.
  Iwahori K, Shintani Y, Funaki S, Yamamoto Y, Matsumoto M, Yoshida T, Morimoto-Okazawa A, Kawashima A, Sato E, Gottschalk S, Okumura M, Kumanogoh A, Wada H.
  Sci Rep. 2019 Feb 22;9(1):2636.
• Impact of sarcopenia in patients with advanced non-small cell lung cancer treated with PD-1 inhibitors: A preliminary retrospective study.
  Shiroyama T, Nagatomo I, Koyama S, Hirata H, Nishida S, Miyake K, Fukushima K, Shirai Y, Mitsui Y, Takata S, Masuhiro K, Yaga M, Iwahori K, Takeda Y, Kida H, Kumanogoh A.
  Sci Rep. 2019 Feb 21;9(1):2447.
• Anti-receptor activator of nuclear factor kappa-B ligand antibody treatment increases osteoclastogenesis-promoting interleukin-8 in patients with rheumatoid arthritis.
  Morita T, Shima Y, Fujimoto K, Tsuboi H, Saeki Y, Narazaki M, Ogata A, Kumanogoh A.
  Int Immunol. 2019 Feb 8. [Epub ahead of print]
• A Phase II Study of Tailored-dose S-1 Plus Carboplatin Followed by Maintenance S-1 for Advanced Squamous Cell Lung Cancer: OSAKA-LCSG 1102.
  Yokoi T, Minami S, Shiroyama T, Koba T, Torii Y, Sugimoto H, Niki M, Mori M, Morimura O, Hirashima T, Komuta K, Kijima T.
  Intern Med. 2019 May 15;58(10):1405-1410. Epub 2019 Feb 1.
• Long-term outcomes of advanced thymoma in patients undergoing preoperative chemotherapy or chemoradiotherapy followed by surgery: a 20-year experience.
  Kanzaki R, Kanou T, Ose N, Funaki S, Shintani Y, Minami M, Kida H, Ogawa K, Kumanogoh A, Okumura M.
  Interact Cardiovasc Thorac Surg. 2019 Mar 1;28(3):360-367.
• Eosinophil-derived neurotoxin enhances airway remodeling in eosinophilic chronic rhinosinusitis and correlates with disease severity.
  Tsuda T, Maeda Y, Nishide M, Koyama S, Hayama Y, Nojima S, Takamatsu H, Okuzaki D, Kinehara Y, Kato Y, Nakatani T, Obata S, Akazawa H, Shikina T, Takeda K, Hayama M, Inohara H, Kumanogoh A.
  Int Immunol. 2019 Feb 6;31(1):33-40.
• Ficolin-1 is a promising therapeutic target for autoimmune diseases.
  Katayama M, Ota K, Nagi-Miura N, Ohno N, Yabuta N, Nojima H, Kumanogoh A, Hirano T.
  Int Immunol. 2019 Feb 6;31(1):23-32.

2018年

• Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer.
  Shintani T, Higashisaka K, Maeda M, Hamada M, Tsuji R, Kurihara K, Kashiwagi Y, Sato A, Obana M, Yamamoto A, Kawasaki K, Lin Y, Kijima T, Kinehara Y, Miwa Y, Maeda S, Morii E, Kumanogoh A, Tsutsumi Y, Nagatomo I, Fujio Y.
  Oncotarget. 2018 Dec 25;9(101):37520-37533.
• Semaphorin 7A promotes EGFR-TKI resistance in EGFR mutant lung adenocarcinoma cells.
  Kinehara Y, Nagatomo I, Koyama S, Ito D, Nojima S, Kurebayashi R, Nakanishi Y, Suga Y, Nishijima-Futami Y, Osa A, Nakatani T, Kato Y, Nishide M, Hayama Y, Higashiguchi M, Morimura O, Miyake K, Kang S, Minami T, Hirata H, Iwahori K, Takimoto T, Takamatsu H, Takeda Y, Hosen N, Hoshino S, Shintani Y, Okumura M, Kumagai T, Nishino K, Imamura F, Nakatsuka SI, Kijima T, Kida H, Kumanogoh A.
  JCI Insight. 2018 Dec 20;3(24).
• Extremely strong infiltration of WT1-specific CTLs into mouse tumor by the combination vaccine with WT1-specific CTL and helper peptides.
  Nakata J, Nakajima H, Hayashibara H, Imafuku K, Morimoto S, Fujiki F, Motooka D, Okuzaki D, Hasegawa K, Hosen N, Tsuboi A, Oka Y, Kumanogoh A, Oji Y, Sugiyama H.
  Oncotarget. 2018 Nov 13;9(89):36029-36038.
• Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity.
  Sakaue S, Hirata J, Maeda Y, Kawakami E, Nii T, Kishikawa T, Ishigaki K, Terao C, Suzuki K, Akiyama M, Suita N, Masuda T, Ogawa K, Yamamoto K, Saeki Y, Matsushita M, Yoshimura M, Matsuoka H, Ikari K, Taniguchi A, Yamanaka H, Kawaji H, Lassmann T, Itoh M, Yoshitomi H, Ito H, Ohmura K, R Forrest AR, Hayashizaki Y, Carninci P, Kumanogoh A, Kamatani Y, de Hoon M, Yamamoto K, Okada Y.
  Nucleic Acids Res. 2018 Dec 14;46(22):11898-11909.
• Phase II trial of induction chemotherapy of pemetrexed plus split-dose cisplatin followed by pemetrexed maintenance for untreated non-squamous non-small-cell lung cancer.
  Koba T, Minami S, Nishijima-Futami Y, Masuhiro K, Kimura H, Futami S, Yaga M, Mori M, Kagawa H, Uenami T, Kohmo S, Otsuka T, Yamamoto S, Komuta K, Kijima T.
  Cancer Chemother Pharmacol. 2018 Jul;82(1):111-117. Epub 2018 May 4.
• SEMA4A promotes eosinophil survival and contributes to eosinophil-mediated allergic diseases.
  Maeda Y, Tsuda T, Takeda Y, Koyama S, Hayama Y, Nojima S, Kimura T, Ito D, Takamatsu H, Kang S, Nishide M, Morimoto K, Hosokawa T, Kinehara Y, Kato Y, Nakatani T, Takeda K, Hayama M, Obata S, Akazawa H, Shikina T, Inohara H, Kumanogoh A.
  Allergol Int. 2019 Apr;68(2):274-276.
• Clinical implications of monitoring nivolumab immunokinetics in non-small cell lung cancer patients.
  Osa A, Uenami T, Koyama S, Fujimoto K, Okuzaki D, Takimoto T, Hirata H, Yano Y, Yokota S, Kinehara Y, Naito Y, Otsuka T, Kanazu M, Kuroyama M, Hamaguchi M, Koba T, Futami Y, Ishijima M, Suga Y, Akazawa Y, Machiyama H, Iwahori K, Takamatsu H, Nagatomo I, Takeda Y, Kida H, Akbay EA, Hammerman PS, Wong KK, Dranoff G, Mori M, Kijima T, Kumanogoh A.
  JCI Insight. 2018 Oct 4;3(19).
• Apoptosis-derived membrane vesicles drive the cGAS-STING pathway and enhance type I IFN production in systemic lupus erythematosus.
  Kato Y, Park J, Takamatsu H, Konaka H, Aoki W, Aburaya S, Ueda M, Nishide M, Koyama S, Hayama Y, Kinehara Y, Hirano T, Shima Y, Narazaki M, Kumanogoh A.
  Ann Rheum Dis. 2018 Oct;77(10):1507-1515.
• The Direct Oblique Method: A New Gold Standard for Bronchoscopic Navigation That is Superior to Automatic Methods.
  Miyake K, Morimura O, Inoue T, Yoshida K, Nagatomo I, Kijima T, Kumanogoh A.
  J Bronchology Interv Pulmonol. 2018 Oct;25(4):305-314.
• Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.
  Kang S, Nakanishi Y, Kioi Y, Okuzaki D, Kimura T, Takamatsu H, Koyama S, Nojima S, Nishide M, Hayama Y, Kinehara Y, Kato Y, Nakatani T, Shimogori T, Takagi J, Toyofuku T, Kumanogoh A.
  Nat Immunol. 2018 Jun;19(6):561-570.
• In vivo visualisation of different modes of action of biological DMARDs inhibiting osteoclastic bone resorption.
  Matsuura Y, Kikuta J, Kishi Y, Hasegawa T, Okuzaki D, Hirano T, Minoshima M, Kikuchi K, Kumanogoh A, Ishii M.
  Ann Rheum Dis. 2018 Aug;77(8):1219-1225.
• Cerebrospinal fluid mitochondrial DNA in neuromyelitis optica spectrum disorder.
  Yamashita K, Kinoshita M, Miyamoto K, Namba A, Shimizu M, Koda T, Sugimoto T, Mori Y, Yoshioka Y, Nakatsuji Y, Kumanogoh A, Kusunoki S, Mochizuki H, Okuno T.
  J Neuroinflammation. 2018 Apr 27;15(1):125.
• Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB.
  Hayama Y, Kimura T, Takeda Y, Nada S, Koyama S, Takamatsu H, Kang S, Ito D, Maeda Y, Nishide M, Nojima S, Sarashina-Kida H, Hosokawa T, Kinehara Y, Kato Y, Nakatani T, Nakanishi Y, Tsuda T, Koba T, Okada M, Kumanogoh A.
  J Immunol. 2018 Jun 1;200(11):3790-3800. Epub 2018 Apr 23.
• Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging.
  Jin Y, Takeda Y, Kondo Y, Tripathi LP, Kang S, Takeshita H, Kuhara H, Maeda Y, Higashiguchi M, Miyake K, Morimura O, Koba T, Hayama Y, Koyama S, Nakanishi K, Iwasaki T, Tetsumoto S, Tsujino K, Kuroyama M, Iwahori K, Hirata H, Takimoto T, Suzuki M, Nagatomo I, Sugimoto K, Fujii Y, Kida H, Mizuguchi K, Ito M, Kijima T, Rakugi H, Mekada E, Tachibana I, Kumanogoh A.
  Sci Rep. 2018 Mar 23;8(1):5145.
• Drug retention and discontinuation reasons between seven biologics in patients with rheumatoid arthritis -The ANSWER cohort study.
  Ebina K, Hashimoto M, Yamamoto W, Ohnishi A, Kabata D, Hirano T, Hara R, Katayama M, Yoshida S, Nagai K, Son Y, Amuro H, Akashi K, Fujimura T, Hirao M, Yamamoto K, Shintani A, Kumanogoh A, Yoshikawa H.
  PLoS One. 2018 Mar 15;13(3):e0194130.
• Beneficial effects of fingolimod in MS patients with high serum Sema4A levels.
  Koda T, Namba A, Nakatsuji Y, Niino M, Miyazaki Y, Sugimoto T, Kinoshita M, Takata K, Yamashita K, Shimizu M, Fukazawa T, Kumanogoh A, Mochizuki H, Okuno T.
  PLoS One. 2018 Mar 8;13(3):e0193986.
• Clinical response to PD-1 blockade correlates with a sub-fraction of peripheral central memory CD4+ T cells in patients with malignant melanoma.
  Takeuchi Y, Tanemura A, Tada Y, Katayama I, Kumanogoh A, Nishikawa H.
  Int Immunol. 2018 Feb 3;30(1):13-22.
• Combination Gemcitabine and WT1 Peptide Vaccination Improves Progression-Free Survival in Advanced Pancreatic Ductal Adenocarcinoma: A Phase II Randomized Study.
  Nishida S, Ishikawa T, Egawa S, Koido S, Yanagimoto H, Ishii J, Kanno Y, Kokura S, Yasuda H, Oba MS, Sato M, Morimoto S, Fujiki F, Eguchi H, Nagano H, Kumanogoh A, Unno M, Kon M, Shimada H, Ito K, Homma S, Oka Y, Morita S, Sugiyama H.
  Cancer Immunol Res. 2018 Jan 22.
• WT1 peptide-based immunotherapy for advanced thymic epithelial malignancies.
  Oji Y, Inoue M, Takeda Y, Hosen N, Shintani Y, Kawakami M, Harada T, Murakami Y, Iwai M, Fukuda M, Nishida S, Nakata J, Nakae Y, Takashima S, Shirakata T, Nakajima H, Hasegawa K, Kida H, Kijima T, Morimoto S, Fujiki F, Tsuboi A, Morii E, Morita S, Sakamoto J, Kumanogoh A, Oka Y, Okumura M, Sugiyama H.
  Int J Cancer. 2018 Jan 11.

2017年

• Efficacy and safety of transbronchial lung biopsy for the diagnosis of lymphangioleiomyomatosis: A report of 24 consecutive patients.
  Koba T, Arai T, Kitaichi M, Kasai T, Hirose M, Tachibana K, Sugimoto C, Akira M, Hayashi S, Inoue Y.
  Respirology. 2018 Mar;23(3):331-338. Epub 2017 Sep 28.
• The activated conformation of integrin β7 is a novel multiple myeloma-specific target for CAR T cell therapy.
  Hosen N, Matsunaga Y, Hasegawa K, Matsuno H, Nakamura Y, Makita M, Watanabe K, Yoshida M, Satoh K, Morimoto S, Fujiki F, Nakajima H, Nakata J, Nishida S, Tsuboi A, Oka Y, Manabe M, Ichihara H, Aoyama Y, Mugitani A, Nakao T, Hino M, Uchibori R, Ozawa K, Baba Y, Terakura S, Wada N, Morii E, Nishimura J, Takeda K, Oji Y, Sugiyama H, Takagi J, Kumanogoh A.
  Nat Med. 2017 Dec;23(12):1436-1443. Epub 2017 Nov 6.
• Quantitative pulmonary blood flow measurement using ₁₅O-H2O PET with and without tissue fraction correction: a comparison study.
  Matsunaga K, Yanagawa M, Otsuka T, Hirata H, Kijima T, Kumanogoh A, Tomiyama N, Shimosegawa E, Hatazawa J.
  EJNMMI Res. 2017 Dec 22;7(1):102.
• Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus.
  Sakakibara S, Arimori T, Yamashita K, Jinzai H, Motooka D, Nakamura S, Li S, Takeda K, Katayama J, El Hussien MA, Narazaki M, Tanaka T, Standley DM, Takagi J, Kikutani H.
  Sci Rep. 2017 Nov 27;7(1):16428.
• Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner.
  Honorat JA, Nakatsuji Y, Shimizu M, Kinoshita M, Sumi-Akamaru H, Sasaki T, Takata K, Koda T, Namba A, Yamashita K, Sanda E, Sakaguchi M, Kumanogoh A, Shirakura T, Tamura M, Sakoda S, Mochizuki H, Okuno T.
  PLoS One. 2017 Nov 6;12(11):e0187215.
• Dendritic cell vaccination as post-remission treatment to prevent or delay relapse in acute myeloid leukemia.
  Anguille S, Van de Velde AL, Smits EL, Van Tendeloo VF, Juliusson G, Cools N, Nijs G, Stein B, Lion E, Driessche AV, Vandenbosch I, Verlinden A, Gadisseur AP, Schroyens WA, Muylle L, Vermeulen K, Maes M-B, Deiteren K, Malfait R, Gostick E, Lammens M, Couttenye MM, Jorens P, Goossens H, Price DA, Ladell K, Oka Y, Fujiki F, Oji Y, Sugiyama H, Berneman ZN.
  Blood. 2017 Oct 12;130 (15):1713-1721. Epub 2017 Aug 22
• Gallbladder-derived surfactant protein D regulates gut commensal bacteria for maintaining intestinal homeostasis.
  Sarashina-Kida H, Negishi H, Nishio J, Suda W, Nakajima Y, Yasui-Kato M, Iwaisako K, Kang S, Endo N, Yanai H, Asagiri M, Kida H, Hattori M, Kumanogoh A, Taniguchi T.
  Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10178-10183. Epub 2017 Sep 6.
• CUBIC pathology: three-dimensional imaging for pathological diagnosis.
  Nojima S, Susaki EA, Yoshida K, Takemoto H, Tsujimura N, Iijima S, Takachi K, Nakahara Y, Tahara S, Ohshima K, Kurashige M, Hori Y, Wada N, Ikeda JI, Kumanogoh A, Morii E, Ueda HR.
  Sci Rep. 2017 Aug 24;7(1):9269.
• Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function.
  Hosokawa T, Kimura T, Nada S, Okuno T, Ito D, Kang S, Nojima S, Yamashita K, Nakatani T, Hayama Y, Kato Y, Kinehara Y, Nishide M, Mikami N, Koyama S, Takamatsu H, Okuzaki D, Ohkura N, Sakaguchi S, Okada M, Kumanogoh A.
  J Immunol. 2017 Sep 15;199(6):2008-2019. Epub 2017 Aug 2.
• Control of species-dependent cortico-motoneuronal connections underlying manual dexterity.
  Gu Z, Kalambogias J, Yoshioka S, Han W, Li Z, Kawasawa YI, Pochareddy S, Li Z, Liu F, Xu X, Wijeratne HRS, Ueno M, Blatz E, Salomone J, Kumanogoh A, Rasin MR, Gebelein B, Weirauch MT, Sestan N, Martin JH, Yoshida Y.
  Science. 2017 Jul 28;357(6349):400-404.
• Carboplatin plus weekly nanoparticle albumin-bound paclitaxel in elderly patients with previously untreated advanced squamous non-small-cell lung cancer selected based on Mini Nutritional Assessment short-form scores: a multicenter phase 2 study.
  Shiroyama T, Tamiya M, Minami S, Takata S, Masuhiro K, Futami-Nishijima Y, Uenami T, Mori M, Koba T, Matsuki T, Takimoto T, Suzuki H, Okamoto N, Komuta K, Hirashima T, Kumanogoh A, Kijima T.
  Cancer Chemother Pharmacol. 2017 Jul 7. [Epub ahead of print]
• Wilms tumour 1 peptide vaccine as a cure-oriented post-chemotherapy strategy for patients with acute myeloid leukaemia at high risk of relapse.
  Nakata J, Nakae Y, Kawakami M, Morimoto S, Motooka D, Hosen N, Fujiki F, Nakajima H, Hasegawa K, Nishida S, Tsuboi A, Oji Y, Oka Y, Kumanogoh A, Sugiyama H.
  Br J Haematol. 2017 May 23. [Epub ahead of print]
• Trastuzumab emtansine suppresses the growth of HER2-positive small-cell lung cancer in preclinical models.
  Morimura O, Minami T, Kijima T, Koyama S, Otsuka T, Kinehara Y, Osa A, Higashiguchi M, Miyake K, Nagatomo I, Hirata H, Iwahori K, Takimoto T, Takeda Y, Kida H, Kumanogoh A.
  Biochem Biophys Res Commun. 2017 Jul 8;488(4):596-602. Epub 2017 May 17.
• Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade.
  Akbay EA, Koyama S, Liu Y, Dries R, Bufe LE, Silkes M, Alam MM, Magee DM, Jones R, Jinushi M, Kulkarni M, Carretero J, Wang X, Warner-Hatten T, Cavanaugh JD, Osa A, Kumanogoh A, Freeman GJ, Awad MM, Christiani DC, Bueno R, Hammerman PS, Dranoff G, Wong KK.
  J Thorac Oncol. 2017 Aug;12(8):1268-1279. Epub 2017 May 6.
• Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis.
  Nishide M, Nojima S, Ito D, Takamatsu H, Koyama S, Kang S, Kimura T, Morimoto K, Hosokawa T, Hayama Y, Kinehara Y, Kato Y, Nakatani T, Nakanishi Y, Tsuda T, Park JH, Hirano T, Shima Y, Narazaki M, Morii E, Kumanogoh A.
  Ann Rheum Dis. 2017 Aug;76(8):1440-1448. Epub 2017 Apr 17.
• Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
  Zhang H, Fillmore Brainson C, Koyama S, Redig AJ, Chen T, Li S, Gupta M, Garcia-de-Alba C, Paschini M, Herter-Sprie GS, Lu G, Zhang X, Marsh BP, Tuminello SJ, Xu C, Chen Z, Wang X, Akbay EA, Zheng M, Palakurthi S, Sholl LM, Rustgi AK, Kwiatkowski DJ, Diehl JA, Bass AJ, Sharpless NE, Dranoff G, Hammerman PS, Ji H, Bardeesy N, Saur D, Watanabe H, Kim CF, Wong KK.
  Nat Commun. 2017 Apr 7;8:14922.
• BATF2 inhibits immunopathological Th17 responses by suppressing Il23a expression during Trypanosoma cruzi infection.
  Kitada S, Kayama H, Okuzaki D, Koga R, Kobayashi M, Arima Y, Kumanogoh A, Murakami M, Ikawa M, Takeda K.
  J Exp Med. 2017 May 1;214(5):1313-1331. Epub 2017 Mar 29.
• Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease.
  Minamitani T, Ma Y, Zhou H, Kida H, Tsai CY, Obana M, Okuzaki D, Fujio Y, Kumanogoh A, Zhao B, Kikutani H, Kieff E, Gewurz BE, Yasui T.
  Proc Natl Acad Sci U S A. 2017 May 2;114(18):4751-4756. Epub 2017 Mar 28.
• Classification of idiopathic interstitial pneumonias using anti-myxovirus resistance-protein 1 autoantibody.
  Hamano Y, Kida H, Ihara S, Murakami A, Yanagawa M, Ueda K, Honda O, Tripathi LP, Arai T, Hirose M, Hamasaki T, Yano Y, Kimura T, Kato Y, Takamatsu H, Otsuka T, Minami T, Hirata H, Inoue K, Nagatomo I, Takeda Y, Mori M, Nishikawa H, Mizuguchi K, Kijima T, Kitaichi M, Tomiyama N, Inoue Y, Kumanogoh A.
  Sci Rep. 2017 Feb 23;7:43201.
• Fungal ITS1 Deep-Sequencing Strategies to Reconstruct the Composition of a 26-Species Community and Evaluation of the Gut Mycobiota of Healthy Japanese Individuals.
  Motooka D, Fujimoto K, Tanaka R, Yaguchi T, Gotoh K, Maeda Y, Furuta Y, Kurakawa T, Goto N, Yasunaga T, Narazaki M, Kumanogoh A, Horii T, Iida T, Takeda K, Nakamura S.
  Front Microbiol. 2017 Feb 15;8:238.
• Predictors of poor sleep quality in patients with systemic lupus erythematosus.
  Inoue M, Shiozawa K, Yoshihara R, Yamane T, Shima Y, Hirano T, Makimoto K.
  Clin Rheumatol. 2017 May;36(5):1053-1062. Epub 2017 Jan 30.

2016年

• Identification of an atypical monocyte and committed progenitor involved in fibrosis.
  Satoh T, Nakagawa K, Sugihara F, Kuwahara R, Ashihara M, Yamane F, Minowa Y, Fukushima K, Ebina I, Yoshioka Y, Kumanogoh A, Akira S.
  Nature. 2017 Jan 5;541(7635):96-101. Epub 2016 Dec 21.
• The Japanese LupusPRO: A cross-cultural validation of an outcome measure for lupus.
  Inoue M, Shiozawa K, Yoshihara R, Yamane T, Shima Y, Hirano T, Jolly M, Makimoto K.
  Lupus. 2017 Jul;26(8):849-856. Epub 2016 Dec 6.
• CAPS1 RNA Editing Promotes Dense Core Vesicle Exocytosis.
  Miyake K, Ohta T, Nakayama H, Doe N, Terao Y, Oiki E, Nagatomo I, Yamashita Y, Abe T, Nishikura K, Kumanogoh A, Hashimoto K, Kawahara Y.
  Cell Rep. 2016 Nov 15;17(8):2004-2014.
• Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine.
  Maeda Y, Kurakawa T, Umemoto E, Motooka D, Ito Y, Gotoh K, Hirota K, Matsushita M, Furuta Y, Narazaki M, Sakaguchi N, Kayama H, Nakamura S, Iida T, Saeki Y, Kumanogoh A, Sakaguchi S, Takeda K.
  Arthritis Rheumatol. 2016 Nov;68(11):2646-2661.
• Clarifying the biological significance of the CHK2 K373E somatic mutation discovered in The Cancer Genome Atlas database.
  Higashiguchi M, Nagatomo I, Kijima T, Morimura O, Miyake K, Minami T, Koyama S, Hirata H, Iwahori K, Takimoto T, Takeda Y, Kida H, Kumanogoh A.
  FEBS Lett. 2016 Dec;590(23):4275-4286. Epub 2016 Oct 25.
• Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals.
  Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, Ito D, Morimoto K, Hosokawa T, Hayama Y, Mitsui Y, Sakurai N, Sarashina-Kida H, Nishide M, Maeda Y, Takamatsu H, Okuzaki D, Yamada M, Okada M, Kumanogoh A.
  Nat Commun. 2016 Oct 12;7:13130.
• Syndecan-4 as a biomarker to predict clinical outcome for glioblastoma multiforme treated with WT1 peptide vaccine.
  Takashima S, Oka Y, Fujiki F, Morimoto S, Nakajima H, Nakae Y, Nakata J, Nishida S, Hosen N, Tatsumi N, Mizuguchi K, Hashimoto N, Oji Y, Tsuboi A, Kumanogoh A, Sugiyama H.
  Future Sci OA. 2016 Oct 3;2(4):FSO96.
• Association of WT1 antibody against WT1 peptide with prolonged survival in glioblastoma multiforme patients vaccinated with WT1 peptide.
  Oji Y, Hashimoto N, Tsuboi A, Murakami Y, Iwai M, Kagawa N, Chiba Y, Izumoto S, Elisseeva O, Ichinohazama R, Sakamoto J, Morita S, Nakajima H, Takashima S, Nakae Y, Nakata J, Kawakami M, Nishida S, Hosen N, Fujiki F, Morimoto S, Adachi M, Iwamoto M, Oka Y, Yoshimine T, Sugiyama H.
  Int J Cancer. 2016 Sep 15;139(6):1391-1401.
• The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis.
  Morita T, Shima Y, Wing JB, Sakaguchi S, Ogata A, Kumanogoh A.
  PLoS One. 2016 Sep 13;11(9):e0162306.
• Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186.
  Fujimoto K, Kinoshita M, Tanaka H, Okuzaki D, Shimada Y, Kayama H, Okumura R, Furuta Y, Narazaki M, Tamura A, Hatakeyama S, Ikawa M, Tsuchiya K, Watanabe M, Kumanogoh A, Tsukita S, Takeda K.
  Mucosal Immunol. 2017 Mar;10(2):446-459. Epub 2016 Jul 6.
• Synergy of radiotherapy and PD-1 blockade in Kras-mutant lung cancer.
  Herter-Sprie GS, Koyama S, Korideck H, Hai J, Deng J, Li YY, Buczkowski KA, Grant AK, Ullas S, Rhee K, Cavanaugh JD, Neupane NP, Christensen CL, Herter JM, Makrigiorgos GM, Hodi FS, Freeman GJ, Dranoff G, Hammerman PS, Kimmelman AC, Wong KK.
  JCI Insight. 2016 Jun 16;1(9):e87415.
• Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies.
  Suzuki K, Tsunoda H, Omiya R, Matoba K, Baba T, Suzuki S, Segawa H, Kumanogoh A, Iwasaki K, Hattori K, Takagi J.
  PLoS One. 2016 Jun 3;11(6):e0156719.
• LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation.
  Morimoto K, Baba Y, Shinohara H, Kang S, Nojima S, Kimura T, Ito D, Yoshida Y, Maeda Y, Sarashina-Kida H, Nishide M, Hosokawa T, Kato Y, Hayama Y, Kinehara Y, Okuno T, Takamatsu H, Hirano T, Shima Y, Narazaki M, Kurosaki T, Toyofuku T, Kumanogoh A.
  Sci Rep. 2016 May 11;6:25738.
• An essential role of the avidity of T cell receptor in differentiation of self-antigen-reactive CD8+ T cells.
  Kondo K, Fujiki F, Nakajima H, Yatsukawa E, Morimoto S, Tatsumi N, Nishida S, Nakata J, Oka Y, Tsuboi A, Hosen N, Oji Y, Sugiyama H.
  J Immunother. 2016 Apr; 39(3): 127-139.
• Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis.
  Ohmi Y, Ise W, Harazono A, Takakura D, Fukuyama H, Baba Y, Narazaki M, Shoda H, Takahashi N, Ohkawa Y, Ji S, Sugiyama F, Fujio K, Kumanogoh A, Yamamoto K, Kawasaki N, Kurosaki T, Takahashi Y, Furukawa K.
  Nat Commun. 2016 Apr 5;7:11205.
• Glycosylation Status of CD43 Protein Is Associated with Resistance of Leukemia Cells to CTL-Mediated Cytolysis.
  Hasegawa K, Tanaka S, Fujiki F, Morimoto S, Nakano K, Kinoshita H, Okumura A, Fujioka Y, Urakawa R, Nakajima H, Tatsumi N, Nakata J, Takashima S, Nishida S, Tsuboi A, Oka Y, Oji Y, Miyoshi E, Hirata T, Kumanogoh A, Sugiyama H, Hosen N.
  PLoS One. 2016 Mar 24;11(3):e0152326.
• Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.
  Koyama S, Akbay EA, Li YY, Herter-Sprie GS, Buczkowski KA, Richards WG, Gandhi L, Redig AJ, Rodig SJ, Asahina H, Jones RE, Kulkarni MM, Kuraguchi M, Palakurthi S, Fecci PE, Johnson BE, Janne PA, Engelman JA, Gangadharan SP, Costa DB, Freeman GJ, Bueno R, Hodi FS, Dranoff G, Wong KK, Hammerman PS.
  Nat Commun. 2016 Feb 17;7:10501.
• STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.
  Koyama S, Akbay EA, Li YY, Aref AR, Skoulidis F, Herter-Sprie GS, Buczkowski KA, Liu Y, Awad MM, Denning WL, Diao L, Wang J, Parra-Cuentas ER, Wistuba II, Soucheray M, Thai T, Asahina H, Kitajima S, Altabef A, Cavanaugh JD, Rhee K, Gao P, Zhang H, Fecci PE, Shimamura T, Hellmann MD, Heymach JV, Hodi FS, Freeman GJ, Barbie DA, Dranoff G, Hammerman PS, Wong KK.
  Cancer Res. 2016 Mar 1;76(5):999-1008. Epub 2016 Feb 1.
• Microarray and whole-exome sequencing analysis of familial Behcet's disease patients.
  Okuzaki D, Yoshizaki K, Tanaka T, Hirano T, Fukushima K, Washio T, Nojima H.
  Sci Rep. 2016 Jan 20;6:19456.

2015年

• An Immunocompetent Mouse Model for MLL/AF9 Leukemia Reveals the Potential of Spontaneous Cytotoxic T-Cell Response to an Antigen Expressed in Leukemia Cells.
  Hasegawa K, Tanaka S, Fujiki F, Morimoto S, Nakajima H, Tatsumi N, Nakata J, Takashima S, Nishida S, Tsuboi A, Oka Y, Oji Y, Kumanogoh A, Sugiyama H, Hosen N.
  PLoS One. 2015 Dec 11;10(12):e0144594.
• Exogenous lipoid pneumonia caused by repeated sesame oil pulling: a report of two cases.
  Kuroyama M, Kagawa H, Kitada S, Maekura R, Mori M, Hirano H.
  BMC Pulm Med. 2015 Oct 30;15:135.
• Transcriptomics Identify CD9 as a Marker of Murine IL-10-Competent Regulatory B Cells.
  Sun J, Wang J, Pefanis E, Chao J, Rothschild G, Tachibana I, Chen JK, Ivanov II, Rabadan R, Takeda Y, Basu U.
  Cell Rep. 2015 Nov 10;13(6):1110-1117. Epub 2015 Oct 29.
• Epiplakin is a Paraneoplastic Pemphigus Autoantigen and Related to Bronchiolitis Obliterans in Japanese Patients.
  Tsuchisaka A, Numata S, Teye K, Natsuaki Y, Kawakami T, Takeda Y, Wang W, Ishikawa K, Goto M, Koga H, Sogame R, Ishii N, Takamori S, Hoshino T, Brandt O, Pas HH, Fujiwara S, Hashimoto T.
  J Invest Dermatol. 2015 Oct 19. [Epub ahead of print]
• Sustainable Efficacy of Switching From Intravenous to Subcutaneous Tocilizumab Monotherapy in Patients With Rheumatoid Arthritis.
  Ogata A, Atsumi T, Fukuda T, Hirabayashi Y, Inaba M, Ishiguro N, Kai M, Kawabata D, Kida D, Kohsaka H, Matsumura R, Minota S, Mukai M, Sumida T, Takasugi K, Tamaki S, Takeuchi T, Ueda A, Yamamoto K, Yamanaka H, Yoshifuji H, Nomura A; Musashi Study Investigators.
  Arthritis Care Res (Hoboken). 2015 Oct;67(10):1354-62.
• Development of Selective Covalent Janus Kinase 3 Inhibitors.
  Tan L, Akahane K, McNally R, Reyskens KM, Ficarro SB, Liu S, Herter-Sprie GS, Koyama S, Pattison MJ, Labella K, Johannessen L, Akbay EA, Wong KK, Frank DA, Marto JA, Look TA, Arthur JS, Eck MJ, Gray NS.
  J Med Chem. 2015 Aug 27;58(16):6589-606. Epub 2015 Aug 18.
• Effectiveness of Tyrosine Kinase Inhibitors in Japanese Patients with Non-small Cell Lung Cancer Harboring Minor Epidermal Growth Factor Receptor Mutations: Results from a Multicenter Retrospective Study (HANSHIN Oncology Group 0212).
  Otsuka T, Mori M, Yano Y, Uchida J, Nishino K, Kaji R, Hata A, Hattori Y, Urata Y, Kaneda T, Tachihara M, Imamura F, Katakami N, Negoro S, Morita S, Yokota S.
  Anticancer Res. 2015 Jul;35(7):3885-91.
• mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells.
  Ito D, Nojima S, Nishide M, Okuno T, Takamatsu H, Kang S, Kimura T, Yoshida Y, Morimoto K, Maeda Y, Hosokawa T, Toyofuku T, Ohshima J, Kamimura D, Yamamoto M, Murakami M, Morii E, Rakugi H, Isaka Y, Kumanogoh A.
  J Immunol. 2015 Aug 1;195(3):934-43. Epub 2015 Jun 26.
• Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation.
  Toyofuku T, Morimoto K, Sasawatari S, Kumanogoh A.
  Mol Cell Biol. 2015 Sep 1;35(17):3044-58. doi: 10.1128/MCB.00085-15. Epub 2015 Jun 22.
• Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation.
  Van Allen EM, Golay HG, Liu Y, Koyama S, Wong K, Taylor-Weiner A, Giannakis M, Harden M, Rojas-Rudilla V, Chevalier A, Thai T, Lydon C, Mach S, Avila AG, Wong JA, Rabin AR, Helmkamp J, Sholl L, Carter SL, Oxnard G, Janne P, Getz G, Lindeman N, Hammerman PS, Garraway LA, Hodi FS, Rodig SJ, Dranoff G, Wong KK, Barbie DA.
  Cancer Immunol Res. 2015 Aug;3(8):855-63. Epub 2015 May 26.
• Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension.
  Hashimoto-Kataoka T, Hosen N, Sonobe T, Arita Y, Yasui T, Masaki T, Minami M, Inagaki T, Miyagawa S, Sawa Y, Murakami M, Kumanogoh A, Yamauchi-Takihara K, Okumura M, Kishimoto T, Komuro I, Shirai M, Sakata Y, Nakaoka Y.
  Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2677-86. Epub 2015 May 4.
• Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair.
  Xia J, Swiercz JM, Banon-Rodriguez I, Matković I, Federico G, Sun T, Franz T, Brakebusch CH, Kumanogoh A, Friedel RH, Martin-Belmonte F, Grone HJ, Offermanns S, Worzfeld T.
  Dev Cell. 2015 May 4;33(3):299-313. Epub 2015 Apr 16.
• Two distinct effector memory cell populations of WT1 (Wilms' tumor gene 1)-specific cytotoxic T lymphocytes in acute myeloid leukemia patients.
  Nakae Y, Oka Y, Fujiki F, Morimoto S, Kamiya T, Takashima S, Nakata J, Nishida S, Nakajima H, Hosen N, Tsuboi A, Kyo T, Oji Y, Mizuguchi K, Kumanogoh A, Sugiyama H.
  Cancer Immunol Immunother. 2015 Jul;64(7):791-804. Epub 2015 Apr 3.
• Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.
  Yoshida Y, Ogata A, Kang S, Ebina K, Shi K, Nojima S, Kimura T, Ito D, Morimoto K, Nishide M, Hosokawa T, Hirano T, Shima Y, Narazaki M, Tsuboi H, Saeki Y, Tomita T, Tanaka T, Kumanogoh A.
  Arthritis Rheumatol. 2015 Jun;67(6):1481-90.
• Wilms tumor 1-peptide vaccination combined with temozolomide against newly diagnosed glioblastoma: safety and impact on immunological response.
  Hashimoto N, Tsuboi A, Chiba Y, Kagawa N, Izumoto S, Kinoshita M, Kijima N, Oka Y, Morimoto S, Nakajima H, Morita S, Sakamoto J, Nishida S, Hosen N, Oji Y, Arita N, Yoshimine T, Sugiyama H.
  Cancer Immunol Immunother. 2015 Jun;64(6):707-716. Epub 2015 Mar 14.
• Longterm Safety and Efficacy of Subcutaneous Tocilizumab Monotherapy: Results from the 2-year Open-label Extension of the MUSASHI Study.
  Ogata A, Amano K, Dobashi H, Inoo M, Ishii T, Kasama T, Kawai S, Kawakami A, Koike T, Miyahara H, Miyamoto T, Munakata Y, Murasawa A, Nishimoto N, Ogawa N, Ojima T, Sano H, Shi K, Shono E, Suematsu E, Takahashi H, Tanaka Y, Tsukamoto H, Nomura A; MUSASHI Study Investigators.
  J Rheumatol. 2015 May;42(5):799-809. Epub 2015 Apr 1.
• Transduction of a novel HLA-DRB1*04:05-restricted, WT1-specific TCR gene into human CD4⁺ T cells confers killing activity against human leukemia cells.
  Katsuhara A, Fujiki F, Aoyama N, Tanii S, Morimoto S, Oka Y, Tsuboi A, Nakajima H, Kondo K, Tatsumi N, Nakata J, Nakae Y, Takashima S, Nishida S, Hosen N, Sogo S, Oji Y, Sugiyama H.
  Anticancer Res. 2015 Mar;35(3):1251-1261.
• Pleuroparenchymal fibroelastosis from a consecutive database: a rare disease entity?
  Nakatani T, Arai T, Kitaichi M, Akira M, Tachibana K, Sugimoto C, Hirooka A, Tsuji T, Minomo S, Hayashi S, Inoue Y.
  Eur Respir J. 2015 Apr;45(4):1183-6. Epub 2015 Feb 19.
• Favorable response to trastuzumab plus irinotecan combination therapy in two patients with HER2-positive relapsed small-cell lung cancer.
  Kinehara Y, Minami T, Kijima T, Hoshino S, Morimura O, Otsuka T, Hayama Y, Fukushima K, Takeuchi Y, Higashiguchi M, Miyake K, Hirata H, Nagatomo I, Inoue K, Takeda Y, Kida H, Kumanogoh A.
  Lung Cancer. 2015 Mar;87(3):321-5. Epub 2015 Jan 10.

2014年

• Semaphorin 4D induces vaginal epithelial cell apoptosis to control mouse postnatal vaginal tissue remodeling.
  Ito T, Bai T, Tanaka T, Yoshida K, Ueyama T, Miyajima M, Negishi T, Kawasaki T, Takamatsu H, Kikutani H, Kumanogoh A, Yukawa K.
  Mol Med Rep. 2015 Feb;11(2):829-36. Epub 2014 Oct 27.
• Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.
  Schulz E, Klampfl P, Holzapfel S, Janecke AR, Ulz P, Renner W, Kashofer K, Nojima S, Leitner A, Zebisch A, Wolfler A, Hofer S, Gerger A, Lax S, Beham-Schmid C, Steinke V, Heitzer E, Geigl JB, Windpassinger C, Hoefler G, Speicher MR, Boland CR, Kumanogoh A, Sill H.
  Nat Commun. 2014 Oct 13;5:5191.
• Opioid switch from low dose of oral oxycodone to transdermal fentanyl matrix patch for patients with stable thoracic malignancy-related pain.
  Minami S, Kijima T, Nakatani T, Yamamoto S, Ogata Y, Hirata H, Shiroyama T, Koba T, Komuta K.
  BMC Palliat Care. 2014 Oct 8;13:46.
• CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcεRIα.
  Kataoka TR, Kumanogoh A, Fukuishi N, Ueshima C, Hirata M, Moriyoshi K, Tsuruyama T, Haga H.
  Int Immunol. 2015 Feb;27(2):95-103. Epub 2014 Sep 19.
• A retrospective study of prognostic factors in patients with interstitial pneumonia receiving long-term oxygen therapy.
  Higashiguchi M, Kijima T, Sumikawa H, Honda O, Minami T, Hirata H, Inoue K, Nagatomo I, Takeda Y, Kida H, Tomiyama N, Kumanogoh A.
  Lung. 2014 Oct;192(5):729-37. doi: 10.1007/s00408-014-9623-4. Epub 2014 Jul 24.
• Estrogen-dependent proteolytic cleavage of semaphorin 4D and plexin-B1 enhances semaphorin 4D-induced apoptosis during postnatal vaginal remodeling in pubescent mice.
  Ito T, Bai T, Tanaka T, Yoshida K, Ueyama T, Miyajima M, Negishi T, Kawasaki T, Takamatsu H, Kikutani H, Kumanogoh A, Yukawa K.
  PLoS One. 2014 May 19;9(5):e97909.
• CD16+CD56+ cells are a potential culprit for hematuria in IgA nephropathy.
  Iwatani H, Nagasawa Y, Yamamoto R, Iio K, Mizui M, Horii A, Kitahara T, Inohara H, Kumanogoh A, Imai E, Rakugi H, Isaka Y.
  Clin Exp Nephrol. 2015 Apr;19(2):216-24. Epub 2014 May 6.
• Comprehensive exploration of autoantibody in Behcet's disease: a novel autoantibody to claudin-1, an essential protein for tight junctions, is identified.
  Morishima A, Hirano T, Nishikawa H, Nakai K, Sakaguchi S, Kumanogoh A.
  Joint Bone Spine. 2014 Dec;81(6):546-8. Epub 2014 Apr 29.
• Plexin-A1 is required for Toll-like receptor-mediated microglial activation in the development of lipopolysaccharide-induced encephalopathy.
  Ito T, Yoshida K, Negishi T, Miyajima M, Takamatsu H, Kikutani H, Kumanogoh A, Yukawa K.
  Int J Mol Med. 2014 May;33(5):1122-30. Epub 2014 Mar 7.
• Phase III study of the efficacy and safety of subcutaneous versus intravenous tocilizumab monotherapy in patients with rheumatoid arthritis.
  Ogata A, Tanimura K, Sugimoto T, Inoue H, Urata Y, Matsubara T, Kondo M, Ueki Y, Iwahashi M, Tohma S, Ohta S, Saeki Y, Tanaka T; Musashi Study Investigators.
  Arthritis Care Res (Hoboken). 2014 Mar;66(3):344-54.
• Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab.
  Shima Y, Hosen N, Hirano T, Arimitsu J, Nishida S, Hagihara K, Narazaki M, Ogata A, Tanaka T, Kishimoto T, Kumanogoh A.
  Mod Rheumatol. 2015 Jan;25(1):134-7. Epub 2014 Feb 18.
• Wilms tumor gene (WT1) peptide-based cancer vaccine combined with gemcitabine for patients with advanced pancreatic cancer.
  Nishida S, Koido S, Takeda Y, Homma S, Komita H, Takahara A, Morita S, Ito T, Morimoto S, Hara K, Tsuboi A, Oka Y, Yanagisawa S, Toyama Y, Ikegami M, Kitagawa T, Eguchi H, Wada H, Nagano H, Nakata J, Nakae Y, Hosen N, Oji Y, Tanaka T, Kawase I, Kumanogoh A, Sakamoto J, Doki Y, Mori M, Ohkusa T, Tajiri H, Sugiyama H.
  J Immunother. 2014 Feb-Mar;37(2):105-14.
• Clinical characteristics and incidence of methotrexate-related lymphoproliferative disorders of patients with rheumatoid arthritis.
  Yoshida Y, Takahashi Y, Yamashita H, Kano T, Kaneko H, Mimori A.
  Mod Rheumatol. 2014 Sep;24(5):763-5. Epub 2014 Feb 5.
• Sema4A inhibits the therapeutic effect of IFN-β in EAE.
  Koda T, Okuno T, Takata K, Honorat JA, Kinoshita M, Tada S, Moriya M, Sakoda S, Mochizuki H, Kumanogoh A, Nakatsuji Y.
  J Neuroimmunol. 2014 Mar 15;268(1-2):43-9. Epub 2014 Jan 7.
• Community-acquired, hospital-acquired, and healthcare-associated pneumonia caused by Pseudomonas aeruginosa.
  Fujii A, Seki M, Higashiguchi M, Tachibana I, Kumanogoh A, Tomono K.
  Respir Med Case Rep. 2014 Mar 26;12:30-3.

2013年

• Phase II trial of pemetrexed continuation--maintenance after carboplatin-based induction in untreated non-squamous non-small cell lung cancer.
  Minami S, Kijima T, Komuta K, Kumagai T, Imamura F, Yokota S, Takeuchi Y, Nakatani T, Tachibana I, Kawase I.
  Anticancer Res. 2013 Dec;33(12):5535-42.
• In vivo eradication of MLL/ENL leukemia cells by NK cells in the absence of adaptive immunity.
  Nakata J, Nakano K, Okumura A, Mizutani Y, Kinoshita H, Iwai M, Hasegawa K, Morimoto S, Fujiki F, Tatsumi N, Nakajima H, Nakae Y, Nishida S, Tsuboi A, Oji Y, Oka Y, Sugiyama H, Kumanogoh A, Hosen N.
  Leukemia. 2014 Jun;28(6):1316-25. Epub 2013 Nov 13.
• Tocilizumab for the treatment of patients with refractory Takayasu arteritis.
  Nakaoka Y, Higuchi K, Arita Y, Otsuki M, Yamamoto K, Hashimoto-Kataoka T, Yasui T, Ikeoka K, Ohtani T, Sakata Y, Shima Y, Kumanogoh A, Yamauchi-Takihara K, Tanaka T, Kishimoto T, Komuro I.
  Int Heart J. 2013;54(6):405-11.
• DNA damage in rheumatoid arthritis: an age-dependent increase in the lipid peroxidation-derived DNA adduct, heptanone-etheno-2'-deoxycytidine.
  Ogawa M, Matsuda T, Ogata A, Hamasaki T, Kumanogoh A, Toyofuku T, Tanaka T.
  Autoimmune Dis. 2013;2013:183487. Epub 2013 Oct 7.
• CD72 regulates the growth of KIT-mutated leukemia cell line Kasumi-1.
  Kataoka TR, Kumanogoh A, Hirata M, Moriyoshi K, Ueshima C, Kawahara M, Tsuruyama T, Haga H.
  Sci Rep. 2013 Oct 4;3:2861.
• Statins decrease lung inflammation in mice by upregulating tetraspanin CD9 in macrophages.
  Jin Y, Tachibana I, Takeda Y, He P, Kang S, Suzuki M, Kuhara H, Tetsumoto S, Tsujino K, Minami T, Iwasaki T, Nakanishi K, Kohmo S, Hirata H, Takahashi R, Inoue K, Nagatomo I, Kida H, Kijima T, Ito M, Saya H, Kumanogoh A.
  PLoS One. 2013 Sep 9;8(9):e73706.
• Overcoming chemoresistance of small-cell lung cancer through stepwise HER2-targeted antibody-dependent cell-mediated cytotoxicity and VEGF-targeted antiangiogenesis.
  Minami T, Kijima T, Kohmo S, Arase H, Otani Y, Nagatomo I, Takahashi R, Miyake K, Higashiguchi M, Morimura O, Ihara S, Tsujino K, Hirata H, Inoue K, Takeda Y, Kida H, Tachibana I, Kumanogoh A.
  Sci Rep. 2013;3:2669.
• Molecular mechanism underlying the antiproliferative effect of suppressor of cytokine signaling-1 in non-small-cell lung cancer cells.
  Shimada K, Serada S, Fujimoto M, Nomura S, Nakatsuka R, Harada E, Iwahori K, Tachibana I, Takahashi T, Kumanogoh A, Kishimoto T, Naka T.
  Cancer Sci. 2013 Nov;104(11):1483-91. Epub 2013 Sep 19.
• A retrospective analysis of 335 Japanese lung cancer patients who responded to initial gefitinib treatment.
  Nishino K, Imamura F, Morita S, Mori M, Komuta K, Kijima T, Namba Y, Kumagai T, Yamamoto S, Tachibana I, Nakazawa Y, Uchida J, Minami S, Takahashi R, Yano Y, Okuyama T, Kumanogoh A.
  Lung Cancer. 2013 Nov;82(2):299-304. Epub 2013 Aug 21.
• Phase II study of pemetrexed plus intermittent erlotinib combination therapy for pretreated advanced non-squamous non-small cell lung cancer with documentation of epidermal growth factor receptor mutation status.
  Minami S, Kijima T, Hamaguchi M, Nakatani T, Koba T, Takahashi R, Takeuchi Y, Kida H, Nagatomo I, Yamamoto S, Tachibana I, Komuta K, Kawase I.
  Lung Cancer. 2013 Nov;82(2):271-5. Epub 2013 Aug 6.
• Maintenance of complete remission after allogeneic stem cell transplantation in leukemia patients treated with Wilms tumor 1 peptide vaccine.
  Maeda T, Hosen N, Fukushima K, Tsuboi A, Morimoto S, Matsui T, Sata H, Fujita J, Hasegawa K, Nishida S, Nakata J, Nakae Y, Takashima S, Nakajima H, Fujiki F, Tatsumi N, Kondo T, Hino M, Oji Y, Oka Y, Kanakura Y, Kumanogoh A, Sugiyama H.
  Blood Cancer J. 2013 Aug 2;3:e130.
• Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.
  Tamaki S, Mano T, Sakata Y, Ohtani T, Takeda Y, Kamimura D, Omori Y, Tsukamoto Y, Ikeya Y, Kawai M, Kumanogoh A, Hagihara K, Ishii R, Higashimori M, Kaneko M, Hasuwa H, Miwa T, Yamamoto K, Komuro I.
  PLoS One. 2013 Jul 19;8(7):e68893.
• Calretinin mediates apoptosis in small cell lung cancer cells expressing tetraspanin CD9.
  He P, Kuhara H, Tachibana I, Jin Y, Takeda Y, Tetsumoto S, Minami T, Kohmo S, Hirata H, Takahashi R, Inoue K, Nagatomo I, Kida H, Kijima T, Naka T, Morii E, Kawase I, Kumanogoh A.
  FEBS Open Bio. 2013 May 10;3:225-30.
• Protection against colitis by CD100-dependent modulation of intraepithelial γδ T lymphocyte function.
  Meehan TF, Witherden DA, Kim CH, Sendaydiego K, Ye I, Garijo O, Komori HK, Kumanogoh A, Kikutani H, Eckmann L, Havran WL.
  Mucosal Immunol. 2014 Jan;7(1):134-42. Epub 2013 May 22.
• Validation of noninvasive morphological and diffusion imaging in mouse emphysema by micro-computed tomography and hyperpolarized (129)Xe magnetic resonance imaging.
  Tetsumoto S, Takeda Y, Imai H, Kimura A, Jin Y, Nakanishi K, Maeda Y, Kuhara H, Tsujino K, Iwasaki T, Shigeta H, Kondo Y, Ito M, Minami T, Hirata H, Takahashi R, Kohmo S, Nagatomo I, Inoue K, Kida H, Kijima T, Tachibana I, Maeda N, Funahashi T, Shimomura I, Fujiwara H, Kumanogoh A.
  Am J Respir Cell Mol Biol. 2013 Oct;49(4):592-600.
• 4D model generator of the human lung, "Lung4Cer".
  Kitaoka H, Koc S, Tetsumoto S, Koumo S, Hirata H, Kijima T.
  Conf Proc IEEE Eng Med Biol Soc. 2013;2013:453-6.
• Polymorphisms of CYP2D6 gene and gefitinib-induced hepatotoxicity.
  Takimoto T, Kijima T, Otani Y, Nonen S, Namba Y, Mori M, Yokota S, Minami S, Komuta K, Uchida J, Imamura F, Furukawa M, Tsuruta N, Fujio Y, Azuma J, Tachibana I, Kumanogoh A.
  Clin Lung Cancer. 2013 Sep;14(5):502-7. Epub 2013 May 9.
• Favorable responses to tocilizumab in two patients with cancer-related cachexia.
  Hirata H, Tetsumoto S, Kijima T, Kida H, Kumagai T, Takahashi R, Otani Y, Inoue K, Kuhara H, Shimada K, Nagatomo I, Takeda Y, Goya S, Yoshizaki K, Kawase I, Tachibana I, Kishimoto T, Kumanogoh A.
  J Pain Symptom Manage. 2013 Aug;46(2):e9-e13.
• HLA-DPB1*05: 01-restricted WT1332-specific TCR-transduced CD4+ T lymphocytes display a helper activity for WT1-specific CTL induction and a cytotoxicity against leukemia cells.
  Lin Y, Fujiki F, Katsuhara A, Oka Y, Tsuboi A, Aoyama N, Tanii S, Nakajima H, Tatsumi N, Morimoto S, Tamanaka T, Tachino S, Hosen N, Nishida S, Oji Y, Kumanogoh A, Sugiyama H.
  J Immunother. 2013 Apr;36(3):159-70.
• Involvement of STAT3 in immune evasion during lung tumorigenesis.
  Kida H, Ihara S, Kumanogoh A.
  Oncoimmunology. 2013 Jan 1;2(1):e22653.
• Retention of tocilizumab and anti-tumour necrosis factor drugs in the treatment of rheumatoid arthritis.
  Hishitani Y, Ogata A, Shima Y, Hirano T, Ebina K, Kunugiza Y, Shi K, Narazaki M, Hagihara K, Tomita T, Yoshikawa H, Tanaka T, Kumanogoh A.
  Scand J Rheumatol. 2013;42(4):253-9. Epub 2013 Mar 7.
• WT1 peptide immunotherapy for gynecologic malignancies resistant to conventional therapies: a phase II trial.
  Miyatake T, Ueda Y, Morimoto A, Enomoto T, Nishida S, Shirakata T, Oka Y, Tsuboi A, Oji Y, Hosen N, Nakatsuka S, Morita S, Sakamoto J, Sugiyama H, Kimura T.
  J Cancer Res Clin Oncol. 2013 Mar;139(3):457-63.
• A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration.
  Nojima S, Toyofuku T, Kamao H, Ishigami C, Kaneko J, Okuno T, Takamatsu H, Ito D, Kang S, Kimura T, Yoshida Y, Morimoto K, Maeda Y, Ogata A, Ikawa M, Morii E, Aozasa K, Takagi J, Takahashi M, Kumanogoh A.
  Nat Commun. 2013;4:1406.
• Echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) rearrangement in congenital pulmonary airway malformation.
  Tetsumoto S, Kijima T, Morii E, Goya S, Minami T, Hirata H, Takahashi R, Kohmo S, Inoue K, Nagatomo I, Takeda Y, Kida H, Tachibana I, Kumanogoh A.
  Clin Lung Cancer. 2013 Jul;14(4):457-60. Epub 2013 Jan 26.
• Dynamic visualization of RANKL and Th17-mediated osteoclast function.
  Kikuta J, Wada Y, Kowada T, Wang Z, Sun-Wada GH, Nishiyama I, Mizukami S, Maiya N, Yasuda H, Kumanogoh A, Kikuchi K, Germain RN, Ishii M.
  J Clin Invest. 2013 Feb;123(2):866-73. Epub 2013 Jan 16.
• Randomized Phase II trial of paclitaxel and carboplatin followed by gemcitabine switch-maintenance therapy versus gemcitabine and carboplatin followed by gemcitabine continuation-maintenance therapy in previously untreated advanced non-small cell lung cancer.
  Minami S, Kijima T, Shiroyama T, Okafuji K, Hirashima T, Uchida J, Imamura F, Osaki T, Nakatani T, Ogata Y, Yamamoto S, Namba Y, Otsuka T, Tachibana I, Komuta K, Kawase I.
  BMC Res Notes. 2013 Jan 3;6:3.

2012年

• Functional human Th17 clones with WT1-specific helper activity.
  Tachino S, Fujiki F, Oka Y, Tsuboi A, Morimoto S, Lin YH, Tamanaka T, Kondo K, Nakajima H, Nishida S, Hosen N, Oji Y, Kumanogoh A, Sugiyama H.
  Cancer Immunol Immunother. 2013 Apr;62(4):801-10. Epub 2012 Dec 29.
• Recognition of a natural WT1 epitope by a modified WT1 peptide-specific T-cell receptor.
  Tamanaka T, Oka Y, Fujiki F, Tsuboi A, Katsuhara A, Nakajima H, Hosen N, Nishida S, Lin YH, Tachino S, Akatsuka Y, Kuzushima K, Oji Y, Kumanogoh A, Sugiyama H.
  Anticancer Res. 2012 Dec;32(12):5201-9.
• Deletion of tetraspanin CD9 diminishes lymphangiogenesis in vivo and in vitro.
  Iwasaki T, Takeda Y, Maruyama K, Yokosaki Y, Tsujino K, Tetsumoto S, Kuhara H, Nakanishi K, Otani Y, Jin Y, Kohmo S, Hirata H, Takahashi R, Suzuki M, Inoue K, Nagatomo I, Goya S, Kijima T, Kumagai T, Tachibana I, Kawase I, Kumanogoh A.
  J Biol Chem. 2013 Jan 25;288(4):2118-31. Epub 2012 Dec 5.
• Pathological role of interleukin-6 in psoriatic arthritis.
  Ogata A, Kumanogoh A, Tanaka T.
  Arthritis. 2012;2012:713618.
• An inhibitory role for Sema4A in antigen-specific allergic asthma.
  Morihana T, Goya S, Mizui M, Yasui T, Prasad DV, Kumanogoh A, Tamura M, Shikina T, Maeda Y, Iwamoto Y, Inohara H, Kikutani H.
  J Clin Immunol. 2013 Jan;33(1):200-9. Epub 2012 Sep 25.
• Phase II tailored S-1 regimen study of first-line chemotherapy in elderly patients with advanced and recurrent non-small cell lung cancer.
  Shiroyama T, Kijima T, Komuta K, Yamamoto S, Minami S, Ogata Y, Okafuji K, Imamura F, Hirashima T, Tachibana I, Kawase I, Kumanogoh A.
  Cancer Chemother Pharmacol. 2012 Dec;70(6):783-9. Epub 2012 Sep 9.
• Suppression of metastases of small cell lung cancer cells in mice by a peptidic CXCR4 inhibitor TF14016.
  Otani Y, Kijima T, Kohmo S, Oishi S, Minami T, Nagatomo I, Takahashi R, Hirata H, Suzuki M, Inoue K, Takeda Y, Kida H, Tachibana I, Fujii N, Kumanogoh A.
  FEBS Lett. 2012 Oct 19;586(20):3639-44. Epub 2012 Aug 28.
• The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function.
  Witherden DA, Watanabe M, Garijo O, Rieder SE, Sarkisyan G, Cronin SJ, Verdino P, Wilson IA, Kumanogoh A, Kikutani H, Teyton L, Fischer WH, Havran WL.
  Immunity. 2012 Aug 24;37(2):314-25. Epub 2012 Aug 16.
• Managing hepatitis B virus carriers with systemic chemotherapy or biologic therapy in the outpatient clinic.
  Nishida T, Hiramatsu N, Mizuki M, Nagatomo I, Kida H, Tazumi K, Shinzaki S, Miyazaki M, Yakushijin T, Tatsumi T, Iijima H, Kiso S, Kanto T, Tsujii M, Takehara T.
  Hepatol Res. 2013 Apr;43(4):339-46. Epub 2012 Aug 6.
• Combination chemotherapy with intermittent erlotinib and pemetrexed for pretreated patients with advanced non-small cell lung cancer: a phase I dose-finding study.
  Minami S, Kijima T, Takahashi R, Kida H, Nakatani T, Hamaguchi M, Takeuchi Y, Nagatomo I, Yamamoto S, Tachibana I, Komuta K, Kawase I.
  BMC Cancer. 2012 Jul 18;12:296.
• Inhibitory roles of signal transducer and activator of transcription 3 in antitumor immunity during carcinogen-induced lung tumorigenesis.
  Ihara S, Kida H, Arase H, Tripathi LP, Chen YA, Kimura T, Yoshida M, Kashiwa Y, Hirata H, Fukamizu R, Inoue R, Hasegawa K, Goya S, Takahashi R, Minami T, Tsujino K, Suzuki M, Kohmo S, Inoue K, Nagatomo I, Takeda Y, Kijima T, Mizuguchi K, Tachibana I, Kumanogoh A.
  Cancer Res. 2012 Jun 15;72(12):2990-9. doi: 10.1158/0008-5472.CAN-11-4062. Epub 2012 Jun 1.
• Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.
  Kuwajima T, Yoshida Y, Takegahara N, Petros TJ, Kumanogoh A, Jessell TM, Sakurai T, Mason C.
  Neuron. 2012 May 24;74(4):676-90.
• Tetraspanin CD151 protects against pulmonary fibrosis by maintaining epithelial integrity.
  Tsujino K, Takeda Y, Arai T, Shintani Y, Inagaki R, Saiga H, Iwasaki T, Tetsumoto S, Jin Y, Ihara S, Minami T, Suzuki M, Nagatomo I, Inoue K, Kida H, Kijima T, Ito M, Kitaichi M, Inoue Y, Tachibana I, Takeda K, Okumura M, Hemler ME, Kumanogoh A.
  Am J Respir Crit Care Med. 2012 Jul 15;186(2):170-80. Epub 2012 May 16.
• Osteoprotection by semaphorin 3A.
  Hayashi M, Nakashima T, Taniguchi M, Kodama T, Kumanogoh A, Takayanagi H.
  Nature. 2012 May 3;485(7396):69-74.
• Elevation of Sema4A implicates Th cell skewing and the efficacy of IFN-β therapy in multiple sclerosis.
  Nakatsuji Y, Okuno T, Moriya M, Sugimoto T, Kinoshita M, Takamatsu H, Nojima S, Kimura T, Kang S, Ito D, Nakagawa Y, Toyofuku T, Takata K, Nakano M, Kubo M, Suzuki S, Matsui-Hasumi A, Uto-Konomi A, Ogata A, Mochizuki H, Sakoda S, Kumanogoh A.
  J Immunol. 2012 May 15;188(10):4858-65. Epub 2012 Apr 9.
• Endosomal sorting by Semaphorin 4A in retinal pigment epithelium supports photoreceptor survival.
  Toyofuku T, Nojima S, Ishikawa T, Takamatsu H, Tsujimura T, Uemura A, Matsuda J, Seki T, Kumanogoh A.
  Genes Dev. 2012 Apr 15;26(8):816-29. Epub 2012 Mar 30.
• CD138-negative clonogenic cells are plasma cells but not B cells in some multiple myeloma patients.
  Hosen N, Matsuoka Y, Kishida S, Nakata J, Mizutani Y, Hasegawa K, Mugitani A, Ichihara H, Aoyama Y, Nishida S, Tsuboi A, Fujiki F, Tatsumi N, Nakajima H, Hino M, Kimura T, Yata K, Abe M, Oka Y, Oji Y, Kumanogoh A, Sugiyama H.
  Leukemia. 2012 Sep;26(9):2135-41. Epub 2012 Mar 20.
• 4-Hydroxy-2-nonenal induces chronic obstructive pulmonary disease-like histopathologic changes in mice.
  Takimoto T, Yoshida M, Hirata H, Kashiwa Y, Takeda Y, Goya S, Kijima T, Kumagai T, Tachibana I, Kawase I.
  Biochem Biophys Res Commun. 2012 Mar 30;420(1):84-90. Epub 2012 Mar 3.
• HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer.
  Minami T, Kijima T, Otani Y, Kohmo S, Takahashi R, Nagatomo I, Hirata H, Suzuki M, Inoue K, Takeda Y, Kida H, Tachibana I, Kumanogoh A.
  Mol Cancer Ther. 2012 Apr;11(4):830-41. Epub 2012 Mar 2.
• CXCL12 as a biological marker for the diagnosis of tuberculous pleurisy.
  Kohmo S, Kijima T, Mori M, Minami T, Namba Y, Yano Y, Yoneda T, Takeda Y, Kitada S, Yamaguchi T, Tachibana I, Yokota S.
  Tuberculosis (Edinb). 2012 May;92(3):248-52. Epub 2012 Jan 30.
• Biased usage of T cell receptor β-chain variable region genes of Wilms' tumor gene (WT1)-specific CD8+ T cells in patients with solid tumors and healthy donors.
  Morimoto S, Oka Y, Tsuboi A, Tanaka Y, Fujiki F, Nakajima H, Hosen N, Nishida S, Nakata J, Nakae Y, Maruno M, Myoui A, Enomoto T, Izumoto S, Sekimoto M, Kagawa N, Hashimoto N, Yoshimine T, Oji Y, Kumanogoh A, Sugiyama H.
  Cancer Sci. 2012 Mar;103(3):408-14. Epub 2012 Jan 17.

2011年

• Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via αvβ1 integrin.
  Kang S, Okuno T, Takegahara N, Takamatsu H, Nojima S, Kimura T, Yoshida Y, Ito D, Ohmae S, You DJ, Toyofuku T, Jang MH, Kumanogoh A.
  J Immunol. 2012 Feb 1;188(3):1108-16. Epub 2011 Dec 23.
• The lactic acid bacterium Pediococcus acidilactici suppresses autoimmune encephalomyelitis by inducing IL-10-producing regulatory T cells.
  Takata K, Kinoshita M, Okuno T, Moriya M, Kohda T, Honorat JA, Sugimoto T, Kumanogoh A, Kayama H, Takeda K, Sakoda S, Nakatsuji Y.
  PLoS One. 2011;6(11):e27644. Epub 2011 Nov 15.
• Control of bone resorption by semaphorin 4D is dependent on ovarian function.
  Dacquin R, Domenget C, Kumanogoh A, Kikutani H, Jurdic P, Machuca-Gayet I.
  PLoS One. 2011;6(10):e26627. Epub 2011 Oct 26.
• Early [18F]fluorodeoxyglucose positron emission tomography at two days of gefitinib treatment predicts clinical outcome in patients with adenocarcinoma of the lung.
  Takahashi R, Hirata H, Tachibana I, Shimosegawa E, Inoue A, Nagatomo I, Takeda Y, Kida H, Goya S, Kijima T, Yoshida M, Kumagai T, Kumanogoh A, Okumura M, Hatazawa J, Kawase I.
  Clin Cancer Res. 2012 Jan 1;18(1):220-8. Epub 2011 Oct 21.
• Ectopic myelinating oligodendrocytes in the dorsal spinal cord as a consequence of altered semaphorin 6D signaling inhibit synapse formation.
  Leslie JR, Imai F, Fukuhara K, Takegahara N, Rizvi TA, Friedel RH, Wang F, Kumanogoh A, Yoshida Y.
  Development. 2011 Sep;138(18):4085-95. Epub 2011 Aug 10.
• The action of Semaphorin7A on thalamocortical axon branching.
  Fukunishi A, Maruyama T, Zhao H, Tiwari M, Kang S, Kumanogoh A, Yamamoto N.
  J Neurochem. 2011 Sep;118(6):1008-15. Epub 2011 Aug 12.
• Favorable response to crizotinib in three patients with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion-type oncogene-positive non-small cell lung cancer.
  Kijima T, Takeuchi K, Tetsumoto S, Shimada K, Takahashi R, Hirata H, Nagatomo I, Hoshino S, Takeda Y, Kida H, Goya S, Tachibana I, Kawase I.
  Cancer Sci. 2011 Aug;102(8):1602-4.
• Two cases of leptomeningeal metastases from lung adenocarcinoma which progressed during gefitinib therapy but responded to erlotinib.
  Tetsumoto S, Osa A, Kijima T, Minami T, Hirata H, Takahashi R, Kuhara H, Nagatomo I, Takeda Y, Kida H, Goya S, Tachibana I, Kawase I.
  Int J Clin Oncol. 2012 Apr;17(2):155-9. Epub 2011 May 19.
• Diminished metastasis in tetraspanin CD151-knockout mice.
  Takeda Y, Li Q, Kazarov AR, Epardaud M, Elpek K, Turley SJ, Hemler ME.
  Blood. 2011 Jul 14;118(2):464-72. Epub 2011 May 2.
• Therapeutic effect of tocilizumab on two patients with polymyositis.
  Narazaki M, Hagihara K, Shima Y, Ogata A, Kishimoto T, Tanaka T.
  Rheumatology (Oxford). 2011 Jul;50(7):1344-6. Epub 2011 Apr 22.
• Recurrent allergic bronchopulmonary aspergillosis in a patient with rheumatoid arthritis treated with etanercept and tocilizumab.
  Honda H, Kida H, Yoshida M, Tomita T, Fujii M, Ihara S, Goya S, Tachibana I, Kawase I.
  Mod Rheumatol. 2011 Dec;21(6):660-4. Epub 2011 Apr 7.
• Phase II study of S-1 monotherapy in platinum-refractory, advanced non-small cell lung cancer.
  Shiroyama T, Komuta K, Imamura F, Hirashima T, Kijima T, Tachibana I, Kawase I.
  Lung Cancer. 2011 Oct;74(1):85-8. Epub 2011 Feb 20.
• Involvement of endothelial apoptosis underlying chronic obstructive pulmonary disease-like phenotype in adiponectin-null mice: implications for therapy.
  Nakanishi K, Takeda Y, Tetsumoto S, Iwasaki T, Tsujino K, Kuhara H, Jin Y, Nagatomo I, Kida H, Goya S, Kijima T, Maeda N, Funahashi T, Shimomura I, Tachibana I, Kawase I.
  Am J Respir Crit Care Med. 2011 May 1;183(9):1164-75. Epub 2011 Jan 14.